Evidence map›Paper›PMID 41803716›Full record

ArticleBMC primary care2026

Integration and scale-up of a primary healthcare-based chronic wound care package for persons affected by skin-neglected tropical diseases and other conditions in Ethiopia: a protocol for an implementation research study.

Mersha Kinfe, Maya Semrau, Asrat Mengiste, Oumer Ali, Tigest Ajeme, Stephen Bremner, Natalia Hounsome, Vasso Anagnostopoulou, Malcolm Brewster, Lawrence Rugema and 4 more

Abstract read
In one paragraph

Article in BMC primary care, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Mersha KinfeCenter for Innovative Drug Development and Therapeutic Trials for Africa (CDT-Africa), Addis Ababa University, Addis Ababa, Ethiopia. mersha35@yahoo.com.
Maya SemrauCentre for Equitable Global Health Research, Department of Global Health and Infection, Brighton and Sussex Medical School, Brighton, BN1 9PX, UK.
Asrat MengisteCenter for Innovative Drug Development and Therapeutic Trials for Africa (CDT-Africa), Addis Ababa University, Addis Ababa, Ethiopia.
Oumer AliCenter for Innovative Drug Development and Therapeutic Trials for Africa (CDT-Africa), Addis Ababa University, Addis Ababa, Ethiopia.
Tigest AjemeCenter for Innovative Drug Development and Therapeutic Trials for Africa (CDT-Africa), Addis Ababa University, Addis Ababa, Ethiopia.
Stephen BremnerDepartment of Primary Care and Public Health, Brighton and Sussex Medical School, Brighton, BN1 9PX, UK.
Natalia HounsomeCentre for Equitable Global Health Research, Department of Global Health and Infection, Brighton and Sussex Medical School, Brighton, BN1 9PX, UK.
Vasso AnagnostopoulouCentre for Equitable Global Health Research, Department of Global Health and Infection, Brighton and Sussex Medical School, Brighton, BN1 9PX, UK.
Malcolm BrewsterFerry Road Health Centre, Rye, East Sussex, UK.
Lawrence RugemaSchool of Public Health, College of Medicine and Health Sciences, University of Rwanda, Kigali, Rwanda.
Eiman Siddig AhmedCentre for Equitable Global Health Research, Department of Global Health and Infection, Brighton and Sussex Medical School, Brighton, BN1 9PX, UK.
Agumasie SemahegnCenter for Innovative Drug Development and Therapeutic Trials for Africa (CDT-Africa), Addis Ababa University, Addis Ababa, Ethiopia.
Abebaw FekaduCenter for Innovative Drug Development and Therapeutic Trials for Africa (CDT-Africa), Addis Ababa University, Addis Ababa, Ethiopia.
Gail DaveyCentre for Equitable Global Health Research, Department of Global Health and Infection, Brighton and Sussex Medical School, Brighton, BN1 9PX, UK.

Funding

National Institute for Health and Care Research NIHR 131996
6 · The paper itself

Abstract

backgroundThe profound impact of wounds on the quality of life of those affected is often underestimated. Chronic wounds impose substantial burdens on individuals and communities in terms of disability, mental distress, stigma, and economic productivity losses. To effectively address these challenges, an integrated and comprehensive approach to primary healthcare-based chronic wound care prevention and management is essential. This implementation research study aims to assess the integration and scale-up of a comprehensive package of primary healthcare-based wound care and psychosocial support for persons affected by chronic wounds caused by NTDs and other conditions in selected districts in Ethiopia.

methodsThe study will be implemented in Central Ethiopia and Amhara Regions in three stages, utilizing a mixed-methods approach to co-develop a comprehensive care package and progressively implement the care package building on learnings from successive stages of implementation. Stage 1 will encompass the co-development of a holistic wound care package and strategies for its integration into routine primary health services. Stage 2 will involve a pilot study in one sub-district, to establish the care package’s adoption, feasibility, acceptability, fidelity, potential effectiveness, readiness for scale-up, and costs. Stage 3 will involve the scale-up of the wound care package and its evaluation in several districts. DISCUSSION: This implementation research on integration and scale up of chronic wound care within primary health services will substantially improve access to care and support for affected persons in Ethiopia. It will also have critical contribution to the national wound care and integrated early detection, management and reporting of chronic wound due to skin-NTDs and other chronic health conditions government initiative in the primary health care system of Ethiopia. The finding from this embedded implementation research will be disseminated to relevant stakeholders using a variety of channels to inform policymaking and program design. Persons affected by chronic wounds and their family, healthcare providers, and program planners will benefit from this study.

Indexed as

Neglected DiseasesPrimary Health CareWounds and InjuriesChronic DiseaseEthiopiaHumansPilot ProjectsChronic woundsEthiopiaLow-income countriesNeglected Tropical DiseasesPrimary healthcare

Identifiers

PMID41803716
PMCPMC13085589

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.