Evidence map›Paper›PMID 41803673›Full record

ArticleThe oncologist2026

Infertility, anxiety, and depression among adolescents and young adults with cancer: the Mexico Cancer Survivorship Registry.

Heidy N Medina, Patricia I Moreno, Frank J Penedo, Johis Ortega, Erika Ruiz-García, Pasquale Patrizio, Oscar Galindo Vázquez

Abstract read
In one paragraph

Article in The oncologist, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Heidy N MedinaSylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL, 33136, United States.ORCID 0000-0002-1999-6448
Patricia I MorenoSylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL, 33136, United States.
Frank J PenedoSylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL, 33136, United States.ORCID 0000-0002-2780-0417
Johis OrtegaSchool of Nursing and Health Studies, University of Miami, Coral Gables, FL, 33146, United States.
Erika Ruiz-GarcíaTranslational Medicine Laboratory and Department of Gastrointestinal Tumors, Instituto Nacional de Cancerología, Mexico City, 14080, Mexico.
Pasquale PatrizioDepartment of Obstetrics, Gynecology, and Reproductive Sciences, University of Miami School of Medicine, Miami, FL, 33136, United States.ORCID 0000-0003-4796-7078
Oscar Galindo VázquezDepartment of Mental Health, Instituto Nacional de Cancerología, Mexico City, 14080, Mexico.

Funding

Training to Reduce Burden across the Cancer Control Continuum (TRACC)T32CA251064 · NCI · UNIVERSITY OF MIAMI CORAL GABLES · PI ERIN N KOBETZ, Frank J Penedo · 2020 to 2026
$3.2M
Training the Next Generation of Global Health Disparities ScientistsT37MD008647 · NIMHD · UNIVERSITY OF MIAMI CORAL GABLES · PI ORTEGA, JOHIS · 2014 to 2024
$2.7M
Patient Activation and Palliative Care among Hispanics/Latinos with Metastatic CancerK01CA258955 · NCI · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI MORENO, PATRICIA INGRID · 2021 to 2025
$834k
HHSNational Cancer Institute career K01CA258955NCI NIH HHS K01 CA258955NCI NIH HHS T32 CA251064NIMHD NIH HHS T37 MD008647NIMHD NIH HHS T37MD008647The Ruth L. Kirschstein NRSA Institution Research Training Grant T32CA251064US Government
6 · The paper itself

Abstract

backgroundIn 2020, 24,000 new cancer cases were diagnosed among adolescents and young adults (AYAs) in Mexico. Cancer-related infertility affects 30%-75% of AYAs and is associated with poor quality of life, relationship satisfaction, and self-worth. This study examines the association between infertility, anxiety, and depression among AYA cancer survivors in Mexico.

methodsData for AYAs (ages 15-39) in the Registro de Supervivientes de Cancer (Cancer Survivor Registry) developed by the Instituto Nacional de Cancerología in Mexico was utilized. A self-report survey was conducted during 2014-2018. Logistic regression models were used to calculate odds ratios (ORs) and corresponding 95% confidence intervals (CIs).

resultsAYA cancer survivors (N = 1168) had a median age of 31 (interquartile range: 25-36), were predominantly women (75%), and 42% had a college education or higher. The most common cancers were breast (33%), lymphoma (12%), cervical (10%), and testicular (9%) with the majority being Stage III (19%) tumors. Approximately 1 in 8 AYAs (12%) reported infertility. Across men and women, after adjusting for age at diagnosis, time since the end of treatment, education level, geographical region, stage, treatment type, and cancer type, AYAs who reported infertility were more likely to experience depression (OR 1.52, 95% CI: 1.02-2.26) symptoms than those who did not report infertility. There was no association between infertility and anxiety among all AYA cancer survivors combined.

conclusionsInfertility is associated with depression symptoms among AYA Mexican cancer survivors. Mexican AYA cancer survivors experiencing infertility may need additional support to address unmet care needs.

Indexed as

AnxietyCancer SurvivorsDepressionInfertilityNeoplasmsAdolescentAdultFemaleHumansMaleMexicoQuality of LifeRegistriesYoung Adultadolescents and young adultsanxietycancer survivordepressiondistressinfertilityMexico

Identifiers

PMID41803673
PMCPMC13006059

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.