SynthesisClinical oral investigations2026
Epidemiological trends in enamel hypomineralisation and molar-incisor hypomineralisation: a systematic review and meta-analysis.
Synthesis in Clinical oral investigations, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
4 authors.
Funding
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Abstract
objectiveRecently, the systematic review and meta-analysis "Epidemiological Trends in Enamel Hypomineralisation and Molar-Incisor Hypomineralisation: A Systematic Review and Meta-Analysis" was published in Clinical Oral Investigations. In 2025 a reader brought the omission of an epidemiological study from North America to the attention of the author group. MATERIALS AND
methodsAfter checking the eligibility for inclusion we aimed at updating the meta-analysis. After inclusion of this overlooked study the systematic review and meta-analysis covers 139 studies and data from a total of 199,999 participants.
resultsFor North America, the MIH prevalence estimate decreased slightly from 0.239 (95% CI: 0.144-0.334) to 0.223 (95% CI: 0.140-0.306). Notably, the global prevalence estimate for MIH remained unchanged at 0.155 (95% CI: 0.144-0.166).
conclusionThe addition of the overlooked study influenced slightly the MIH outcome for North America but had no impact on the previously drawn conclusions. CLINICAL RELEVANCE: Enamel hypomineralisation/ Molar incisor hypomineralisation is prevalent across the globe and needs attention by dental practitioners.
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