Evidence map›Paper›PMID 41803449›Full record

SynthesisNature food2026

Grain zinc, iron and protein concentrations of contemporary wheat cultivars fall short of targets for human health.

Mina Devkota, Gudeta W Sileshi, Kalimuthu Senthilkumar, Martin R Broadley, Dominic Mutambu, Andrew Sila, Krishna Devkota, Govinda Rizal, Job Kihara

Abstract readMeta-Analysis
In one paragraph

Synthesis in Nature food, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Mina DevkotaInternational Center for Agricultural Research in the Dry Areas (ICARDA), Rabat, Morocco. m.devkota@cgiar.org.ORCID 0000-0002-2348-4816
Gudeta W SileshiDepartment of Plant Biology and Biodiversity Management, Addis Ababa University, Addis Ababa, Ethiopia.ORCID 0000-0001-7828-6238
Kalimuthu SenthilkumarAfrica Rice Center (AfricaRice), Antananarivo, Madagascar.ORCID 0000-0002-2862-411X
Martin R BroadleyRothamsted Research, Harpenden, UK.
Dominic MutambuInternational Center for Tropical Agriculture (CIAT), ICIPE Duduville Complex, Nairobi, Kenya.
Andrew SilaInternational Center for Tropical Agriculture (CIAT), ICIPE Duduville Complex, Nairobi, Kenya.
Krishna DevkotaInternational Center for Agricultural Research in the Dry Areas (ICARDA), Rabat, Morocco.
Govinda RizalInternational Center for Agricultural Research in the Dry Areas (ICARDA), Rabat, Morocco.
Job KiharaInternational Center for Tropical Agriculture (CIAT), ICIPE Duduville Complex, Nairobi, Kenya.

Funding

Bill and Melinda Gates Foundation (Bill & Melinda Gates Foundation) CGIAR
6 · The paper itself

Abstract

Grain zinc (Zn), iron (Fe) and protein concentrations have declined in wheat cultivars released since the 1960s. Here we conducted a meta-analysis of field studies to provide a global synthesis of how genetic, environmental and agronomic factors influence grain Zn, Fe and protein concentrations. The probability of achieving the Zn target (38 mg kg

Indexed as

Edible GrainIronPlant ProteinsTriticumZincBiofortificationFertilizersHumansFertilizersIronPlant ProteinsZinc

Identifiers

PMID41803449
PMCPMC13021525

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.