Evidence map›Paper›PMID 41803430›Full record

ArticleNeurocritical care2026

Time-Dependent Relationship between Blood Pressure Trajectory and Functional Outcomes after Endovascular Thrombectomy.

Kyubong Lee, Jung Hoon Han, Chi Kyung Kim, Jeong Yoon Song, Hyunsun Oh, Keonyeup Kim, Wookjin Yang, Jun Young Chang, Dong-Wha Kang, Sun U Kwon and 7 more

Abstract read
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Article in Neurocritical care, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Kyubong Lee *Department of Neurology, Korea University Guro Hospital, Korea University College of Medicine, Seoul, Republic of Korea.
Jung Hoon Han *Department of Neurology, Uijeongbu Eulji Medical Center, Eulji University School of Medicine, Uijeongbu, Republic of Korea.
Chi Kyung KimDepartment of Neurology, Korea University Guro Hospital, Korea University College of Medicine, Seoul, Republic of Korea.
Jeong Yoon SongDepartment of Neurology, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympic-Ro 43-Gil, Songpa-Gu, Seoul, South Korea.
Hyunsun OhDepartment of Neurology, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympic-Ro 43-Gil, Songpa-Gu, Seoul, South Korea.
Keonyeup KimDepartment of Neurology, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympic-Ro 43-Gil, Songpa-Gu, Seoul, South Korea.
Wookjin YangDepartment of Neurology, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympic-Ro 43-Gil, Songpa-Gu, Seoul, South Korea.
Jun Young ChangDepartment of Neurology, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympic-Ro 43-Gil, Songpa-Gu, Seoul, South Korea.
Dong-Wha KangDepartment of Neurology, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympic-Ro 43-Gil, Songpa-Gu, Seoul, South Korea.
Sun U KwonDepartment of Neurology, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympic-Ro 43-Gil, Songpa-Gu, Seoul, South Korea.
Seon Moon HwangDepartment of Radiology, Research Institute of Radiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.
Joon Ho ChoiDepartment of Radiology, Research Institute of Radiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.
Boseong KwonDepartment of Radiology, Research Institute of Radiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.
Yunsun SongDepartment of Radiology, Research Institute of Radiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.
Deok Hee LeeDepartment of Radiology, Research Institute of Radiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.
Sehee KimDepartment of Clinical Epidemiology and Biostatistics, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Republic of Korea.
Bum Joon KimDepartment of Neurology, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympic-Ro 43-Gil, Songpa-Gu, Seoul, South Korea. medicj80@hanmail.net.ORCID 0000-0002-3278-3252

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe prognostic significance of spontaneous systolic blood pressure (SBP) reduction following endovascular thrombectomy (EVT) remains unclear, especially according to the timing of measurement. The optimal timing for initiating antihypertensive therapy in patients with elevated SBP after reperfusion is also uncertain.

methodsWe retrospectively analyzed 349 patients with acute ischemic stroke due to large vessel occlusion who underwent EVT between 2015 and 2024. SBP was recorded from the time of arrival at the emergency department through 24 h post-procedure. Patients were classified on the basis of whether their SBP dropped below 140 mm Hg immediately after recanalization or upon admission to the intensive care unit within 1 h after EVT (after stabilization). Use of BP-lowering agents administered immediately after recanalization was also recorded and analyzed. The primary outcome was good functional status (modified Rankin scale score 0-2) at 3 months.

resultsAmong the 349 patients (mean age: 71.4 ± 10.4 years; 56.2% male), 45.0% had a mean SBP of less than 140 mm Hg immediately following recanalization. While SBP < 140 mm Hg immediately following recanalization did not show a significant association with the primary outcome, SBP < 140 mm Hg measured after stabilization (within 1 h post-EVT) was independently associated with good outcomes (adjusted odds ratio 6.92, 95% confidence interval 2.47-19.43, P < 0.001). The use of BP-lowering agents among those with elevated SBP immediately after recanalization did not show an independent association with the primary outcome.

conclusionsSBP < 140 mm Hg after stabilization following EVT, rather than immediately after recanalization, was associated with good functional outcomes, regardless of the use of BP-lowering agents immediately after recanalization.

Indexed as

Antihypertensive AgentsBlood PressureEndovascular ProceduresFunctional StatusHypertensionIschemic StrokeOutcome Assessment, Health CareThrombectomyAgedAged, 80 and overFemaleHumansMaleMiddle AgedRetrospective StudiesTime FactorsAntihypertensive Agents

Identifiers

PMID41803430

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.