Evidence map›Paper›PMID 41803353›Full record

ArticleSurgical endoscopy2026

Age-dependent trade-offs between tubular esophagogastric and double-tract anastomosis after laparoscopic proximal gastrectomy: a retrospective cohort study.

Meng Wei, Zepeng Yan, Zewei Cheng, Chaoqun Wang, Jun Ouyang, Yadi Huang, Chuanqi Chen, Menghui Wang, Yongqi Yan, Yangjia Li and 4 more

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Surgical endoscopy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

14 authors.

Meng Wei *Department of Gastrointestinal Surgery, General Surgery, Qilu Hospital, Cheeloo College of Medicine, Shandong University, West Wenhua Rd, Shandong, 250012, China.
Zepeng Yan *Department of Gastrointestinal Surgery, General Surgery, Qilu Hospital, Cheeloo College of Medicine, Shandong University, West Wenhua Rd, Shandong, 250012, China.
Zewei ChengDepartment of Gastrointestinal Surgery, General Surgery, Qilu Hospital, Cheeloo College of Medicine, Shandong University, West Wenhua Rd, Shandong, 250012, China.
Chaoqun WangCheeloo College of Medicine, Shandong University, Jinan, China.
Jun OuyangDepartment of Gastrointestinal Surgery, General Surgery, Qilu Hospital, Cheeloo College of Medicine, Shandong University, West Wenhua Rd, Shandong, 250012, China.
Yadi HuangTengzhou Central People's Hospital, Zaozhuang, China.
Chuanqi ChenDepartment of Gastrointestinal Surgery, General Surgery, Qilu Hospital, Cheeloo College of Medicine, Shandong University, West Wenhua Rd, Shandong, 250012, China.
Menghui WangDepartment of Gastrointestinal Surgery, General Surgery, Qilu Hospital, Cheeloo College of Medicine, Shandong University, West Wenhua Rd, Shandong, 250012, China.
Yongqi YanDepartment of Gastrointestinal Surgery, General Surgery, Qilu Hospital, Cheeloo College of Medicine, Shandong University, West Wenhua Rd, Shandong, 250012, China.
Yangjia LiDepartment of Gastrointestinal Surgery, General Surgery, Qilu Hospital, Cheeloo College of Medicine, Shandong University, West Wenhua Rd, Shandong, 250012, China.
Honglei WangDepartment of Gastrointestinal Surgery, General Surgery, Qilu Hospital, Cheeloo College of Medicine, Shandong University, West Wenhua Rd, Shandong, 250012, China.
Yihang XuDepartment of Gastrointestinal Surgery, General Surgery, Qilu Hospital, Cheeloo College of Medicine, Shandong University, West Wenhua Rd, Shandong, 250012, China.
Zhibo YanDepartment of Gastrointestinal Surgery, General Surgery, Qilu Hospital, Cheeloo College of Medicine, Shandong University, West Wenhua Rd, Shandong, 250012, China.
Wenbin YuDepartment of Gastrointestinal Surgery, General Surgery, Qilu Hospital, Cheeloo College of Medicine, Shandong University, West Wenhua Rd, Shandong, 250012, China. wenbin_yu2003@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOptimal reconstruction after laparoscopic proximal gastrectomy (LPG) remains debated. This study compared perioperative outcomes and long-term quality of life (QoL) between tubular esophagogastric (TEG) and double-tract (DT) anastomosis, with attention to age-dependent effects.

methodsThis retrospective cohort study included 284 patients undergoing LPG with TEG or DT. Exploratory age-stratified analyses were performed. QoL was evaluated using GerdQ, dysphagia scores, and the Postgastrectomy Syndrome Assessment Scale-45 (PGSAS-45).

resultsDT was associated with longer operative time than TEG (232.1 vs 217.6 min, P = 0.016), primarily due to prolonged reconstruction time (90.3 vs 66.0 min, P < 0.001). In an exploratory analysis of patients aged ≥ 70 years, TEG was associated with fewer overall complications than DT (25.9% vs 50.0%, P = 0.049), while complication severity by Clavien-Dindo grade was comparable between groups. This divergence was primarily attributable to non-anastomosis-related complications rather than anastomotic events. In multivariable analysis within the ≥ 70-year subgroup, DT (vs TEG) remained independently associated with postoperative complications (OR 3.57, 95% CI 1.03-12.41; P = 0.045). Conversely, DT demonstrated superior anti-reflux outcomes, including lower GerdQ scores and lower reflux esophagitis rates at 12 and 24 months (all P < 0.05). DT also showed lower anastomotic stenosis at 3 months (4.0% vs 11.4%, P = 0.038) and better long-term QoL regarding food intake and meal-related distress.

conclusionsDT offers superior reflux control and long-term QoL outcomes. However, in patients aged ≥ 70 years, TEG demonstrated a perioperative safety advantage, driven mainly by a lower rate of non-anastomosis-related complications. Reconstruction choice in older patients should be individualized by balancing perioperative risks and long-term functional benefits.

Indexed as

EsophagusGastrectomyLaparoscopyStomach NeoplasmsAgedAged, 80 and overAge FactorsAnastomosis, SurgicalFemaleHumansMaleMiddle AgedOperative TimePostoperative ComplicationsQuality of LifeRetrospective StudiesDouble-tract anastomosisElderly patientsGastric cancerLaparoscopic proximal gastrectomyTubular esophagogastric anastomosis

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.