ArticleSpinal cord2026
Wearable powered overground exoskeleton reduces dose-dependently the spasticity in individuals with spinal cord injury.
Article in Spinal cord, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Robotic Rehabilitation in Spinal Cord Injury: Neurophysiological Basis and Severity-Based Clinical Framework.Brain sciences · 2026Review
- Robotic-Assisted Rehabilitation and Spinal Neuromodulation After Spinal Cord Injury: From Mechanisms to Trial-Informed Practice.Journal of clinical medicine · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
STUDY
designA multicenter retrospective pre-post cohort study.
objectiveThis study aimed to evaluate the dose-dependent effects of overground exoskeleton-assisted gait training on spasticity and functional independence in individuals with SCI.
settingIRCCS San Raffaele Rome, San Raffaele Sulmona, Centro Neurolesi Bonino Pulejo IRCCS in Messina, and Montecatone Rehabilitation Institute in Imola.
methodsSeventy-four participants with SCI underwent a minimum of five gait training sessions using the Ekso™ exoskeleton. Primary outcomes included changes in spasticity, measured via the aggregated Modified Ashworth Scale (MAS), and functional independence, assessed by the Spinal Cord Independence Measure (SCIM) III. Secondary analyses explored the influence of treatment dosage.
resultsSignificant reductions in spasticity were observed across all muscle groups (proximal, intermediate, and distal) post-intervention (p < 0.0001). SCIM scores also showed substantial improvements (p < 0.0001), indicating enhanced functional independence. Participants receiving ≥15 sessions demonstrated greater gains compared to those with fewer sessions (p < 0.05).
conclusionsOverground exoskeleton-assisted gait training effectively reduces spasticity and improves functional independence in individuals with SCI, with greater benefits observed at higher session frequencies. These findings support the integration of wearable powered exoskeletons into standard rehabilitation protocols for SCI.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.