Evidence map›Paper›PMID 41802870›Full record

ArticleMolecular plant pathology2026

Functional Dissection of a Wheat NLR Protein Reveals a Minimal Active Region and Key Regulatory Sites for Immune Signalling.

Xiaoxu Zhu, Shuo Jiang, Jinchen Zhao, Fangfang Peng, Ran Zhao, Xinnuo Li, Yi Luo, Zhihao Xiong, Qi Li, Filip Rolland and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular plant pathology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Xiaoxu ZhuCollege of Life Sciences and State Key Laboratory for Crop Stress Resistance and High-Efficiency Production, Northwest A&F University, Yangling, Shaanxi, China.
Shuo JiangCollege of Life Sciences and State Key Laboratory for Crop Stress Resistance and High-Efficiency Production, Northwest A&F University, Yangling, Shaanxi, China.
Jinchen ZhaoCollege of Life Sciences and State Key Laboratory for Crop Stress Resistance and High-Efficiency Production, Northwest A&F University, Yangling, Shaanxi, China.
Fangfang PengCollege of Life Sciences and State Key Laboratory for Crop Stress Resistance and High-Efficiency Production, Northwest A&F University, Yangling, Shaanxi, China.
Ran ZhaoCollege of Natural Resources and Environment and State Key Laboratory for Crop Stress Resistance and High-Efficiency Production, Northwest A&F University, Yangling, Shaanxi, China.
Xinnuo LiCollege of Life Sciences and State Key Laboratory for Crop Stress Resistance and High-Efficiency Production, Northwest A&F University, Yangling, Shaanxi, China.
Yi LuoCollege of Life Sciences and State Key Laboratory for Crop Stress Resistance and High-Efficiency Production, Northwest A&F University, Yangling, Shaanxi, China.
Zhihao XiongCollege of Life Sciences and State Key Laboratory for Crop Stress Resistance and High-Efficiency Production, Northwest A&F University, Yangling, Shaanxi, China.
Qi LiCollege of Life Sciences and State Key Laboratory for Crop Stress Resistance and High-Efficiency Production, Northwest A&F University, Yangling, Shaanxi, China.
Filip RollandLaboratory for Plant Metabolic Signaling, Biology Department, and KU Leuven Plant Institute, Leuven, Belgium.
Zhensheng KangCollege of Plant Protection and State Key Laboratory for Crop Stress Resistance and High-Efficiency Production, Northwest A&F University, Yangling, Shaanxi, China.
Xiaojie WangCollege of Plant Protection and State Key Laboratory for Crop Stress Resistance and High-Efficiency Production, Northwest A&F University, Yangling, Shaanxi, China.ORCID 0000-0001-9968-0373
Yunqi LiuZhongguancun Xuyue Non-Invasive Micro-Test Technology Industrial Alliance, Beijing, China.
Li HuangDepartment of Plant Sciences and Plant Pathology, Montana State University, Bozeman, Montana, USA.
Xiaojing WangCollege of Life Sciences and State Key Laboratory for Crop Stress Resistance and High-Efficiency Production, Northwest A&F University, Yangling, Shaanxi, China.ORCID 0009-0003-1616-9134

Funding

College Students' innovation and entrepreneurship training program S202410712456College Students' innovation and entrepreneurship training program X202410712637National Key Research and Development Program of China 2021YFD1401000National Key Research and Development Program of China 2022YFF1001500National Natural Science Foundation of China 31501619National Natural Science Foundation of China 32172424Natural Science Foundation of Shaanxi Province 2021JM095University of Sydney
6 · The paper itself

Abstract

Nucleotide-binding site (NBS) leucine-rich repeat (LRR) receptors (NLRs) are crucial for plant immunity but often come with trade-offs in plant growth. Understanding the mechanisms of their self-regulating activity for controlled immune responses is essential for optimising crop resistance. In this study, we investigated the activity fine-tuning of the wheat NLR protein NLR

Indexed as

NLR ProteinsPlant ImmunityPlant ProteinsSignal TransductionTriticumAmino Acid SequenceCell DeathDisease ResistanceNicotianaPlant DiseasesProtein DomainsReactive Oxygen SpeciesNLR ProteinsPlant ProteinsReactive Oxygen SpeciesCC domaincell deathLRR domainNBS domainNLRsplant immunity

Identifiers

PMID41802870
PMCPMC12971249

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.