Evidence map›Paper›PMID 41802845›Full record

ArticlePediatric dermatology

Oral JAK Inhibitors in Pediatric Generalized Vitiligo Resistant to Conventional Treatment: A Case Series.

Andrés Vidal González, Rafael Escudero Tornero, Sergio López Alcázar, Rocio Maseda Pedrero, Marta Feito Rodríguez, Raúl De Lucas Laguna

Abstract readCase Reports
In one paragraph

Article in Pediatric dermatology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Andrés Vidal GonzálezDermatology, Hospital Universitario La Paz, Madrid, Spain.ORCID https://orcid.org/0009-0001-0492-0969
Rafael Escudero TorneroDermatology, Hospital Universitario La Paz, Madrid, Spain.ORCID https://orcid.org/0000-0002-1652-0823
Sergio López AlcázarDermatology, Hospital Universitario La Paz, Madrid, Spain.
Rocio Maseda PedreroDermatology, Hospital Universitario La Paz, Madrid, Spain.
Marta Feito RodríguezDermatology, Hospital Universitario La Paz, Madrid, Spain.ORCID https://orcid.org/0000-0002-2645-8904
Raúl De Lucas LagunaDermatology, Hospital Universitario La Paz, Madrid, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pediatric generalized vitiligo resistant to conventional therapy remains a major therapeutic challenge. We report four children treated with oral JAK inhibitors achieving marked repigmentation without significant adverse effects. Improvement often began within months, particularly when combined with phototherapy. These findings suggest systemic JAK inhibition as a promising option for refractory pediatric vitiligo.

Indexed as

AzetidinesJanus Kinase InhibitorsSulfonamidesVitiligoAdministration, OralAdolescentChildChild, PreschoolFemaleHumansMalePurinesPyrazolesTreatment OutcomeAzetidinesbaricitinibJanus Kinase InhibitorsPurinesPyrazolesSulfonamidesbaricitinibJAK inhibitorupadacitinibvitiligo

Identifiers

PMID41802845
PMCPMC13422993

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.