Evidence map›Paper›PMID 41802321›Full record

ArticleUltrasonography (Seoul, Korea)2026

Ultrasound-guided ablation of hepatocellular carcinoma: a review of its past, present, and future.

Kyowon Gu, Hyunchul Rhim, Min Woo Lee, Seungchul Han

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Ultrasonography (Seoul, Korea), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Kyowon GuDepartment of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Hyunchul RhimDepartment of Radiology, Samsung Changwon Hospital, Sungkyunkwan University School of Medicine, Changwon, Korea.
Min Woo LeeDepartment of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Seungchul HanDepartment of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ultrasound (US)-guided ablation has evolved from early ethanol injection into a cornerstone curative strategy for hepatocellular carcinoma. This review traces the technological advancement of US guidance from early pioneering efforts to present standardized techniques and future innovations. It discusses how modern tools-fusion imaging, contrast-enhanced US, and artificial fluid techniques-overcome challenges in tumor visibility and accessibility, emphasizing technique optimization rather than energy modality selection. The review also explores future horizons, including artificial intelligence-driven planning, histotripsy, and immuno-ablation. Ultimately, the authors advocate for a philosophy of "optimized ablation," prioritizing technical mastery of evolving US technologies to maximize therapeutic efficacy and patient safety beyond simple expansion of treatment territory.

Indexed as

CryosurgeryHepatocellular carcinomaHigh-intensity focused ultrasound ablationInterventional ultrasonographyRadiofrequency ablation

Identifiers

PMID41802321
PMCPMC12971156

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.