Evidence map›Paper›PMID 41802142›Full record

ArticlePublic health genomics2026

Implementing Genomic Medicine in a Federally Qualified Health Center: Assessing Readiness through a Mixed-Methods Approach.

Emory William Heffernan, Paramita Das, Larry Hearld, Catanya G Stager, Samantha Whitfield, Irene Moss, Tiffany Osborne, Alex Zayzafoon, Christopher Mosely, Bruce Korf and 2 more

Abstract read
In one paragraph

Article in Public health genomics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Emory William HeffernanDepartment of Neurology, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Paramita DasDepartment of Medicine, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Larry HearldDepartment of Health Services Administration, School of Health Professions, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Catanya G StagerDepartment of Medicine, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA, cgstager@uabmc.edu.
Samantha WhitfieldDepartment of Medicine, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Irene MossCystic Fibrosis Research Center, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Tiffany OsborneDepartment of Medicine, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Alex ZayzafoonDepartment of Medicine, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Christopher MoselyAlabama Regional Medical Services, Birmingham, Alabama, USA.
Bruce KorfDepartment of Genetics, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Nita LimdiDepartment of Neurology, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Lori Brand BatemanDepartment of Medicine, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA.

Funding

CTSA UM1 at the University of Alabama at BirminghamUM1TR004771 · NCATS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI PATRICE DELAFONTAINE, Orlando M Gutierrez · 2024 to 2026
$29.2M
CTSA Postdoctoral T32 at the University of Alabama at BirminghamT32TR004770 · NCATS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Bertha Hidalgo · 2024 to 2026
$1.3M
Patient Oriented Research in Personalized Antithrombotic TherapyK24HL133373 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI LIMDI, NITA A · 2016 to 2025
$1.2M
NCATS NIH HHS T32 TR004770NCATS NIH HHS UM1 TR004771NHLBI NIH HHS K24 HL133373
6 · The paper itself

Abstract

introductionGenomic medicine enables early detection of treatable conditions and supports personalized care across all populations; however, evidence guiding its implementation in resource-constrained healthcare settings remains limited.

methodsUsing a mixed-methods approach, this study evaluated the readiness of an Alabama Federally Qualified Health Center (FQHC) to implement genomic medicine as part of routine clinical care. Staff members (e.g., physicians, nurses, medical assistants, and administrators) completed surveys, individual interviews, a concept mapping session, and a nominal group technique exercise.

resultsStudy participants included 13 clinic members. Interviews and mapping revealed three dominant barriers: staffing shortages, financial constraints, and language obstacles. Facilitators included a strong commitment to quality care, alignment with the clinical mission, and supportive leadership. Survey results (N = 12) revealed mean scores in the positive range for culture, learning climate, and leadership engagement, whereas scores for stress, available resources, and readiness for change were nearer to the neutral midpoint, suggesting potential practical constraints on genomic implementation. The use of the CFIR-ERIC Implementation Strategy Matching Tool allowed the team and participants to evaluate nine candidate strategies, prioritizing those with high feasibility and impact. The evaluation was visually developed into an impact matrix which placed patient and family involvement, tailored educational materials, educational meetings, and designated genomic medicine leadership in the high-feasibility/high-impact quadrant. These strategies directly address identified barriers and fit existing clinical strengths, which is important for equitable precision-medicine adoption.

conclusionFindings indicate that FQHCs can advance genomic services through culturally attuned patient engagement, structured provider training, and clear leadership roles.

Indexed as

Genomic MedicineAlabamaHumansLeadershipSurveys and QuestionnairesCFIR frameworkFederally Qualified Health CentersGenomic medicineHealth equityImplementation scienceMixed methods

Identifiers

PMID41802142
PMCPMC13087925

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.