Evidence map›Paper›PMID 41801990›Full record

ArticleHaemophilia : the official journal of the World Federation of Hemophilia

National Bleeding Disorder Foundation Clinical Practice Recommendations for Laboratory Screening of Iron Deficiency With and Without Anemia in the Inherited Bleeding Disorders Population.

Glaivy Batsuli, Magdalena D Lewandowska, Ming Y Lim, Kelly Tickle, Maureen K Baldwin, Rose Bender, Jennifer Davila, Brendan Hayes, Amanda Jacobson-Kelly, Peter Kouides and 6 more

Abstract read
In one paragraph

Article in Haemophilia : the official journal of the World Federation of Hemophilia. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

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0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Glaivy BatsuliDepartment of Pediatrics, Stanford University, Palo Alto, California, USA.
Magdalena D LewandowskaInnovative Hematology/Indiana Hemophilia & Thrombosis Center, Indianapolis, Indiana, USA.
Ming Y LimDivision of Hematology and Hematologic Malignancies, Department of Internal Medicine, University of Utah, Salt Lake City, Utah, USA.
Kelly TickleHemophilia of Georgia Center For Bleeding and Clotting Disorders At Children's Healthcare of Atlanta, Atlanta, Georgia, USA.
Maureen K BaldwinDepartment of Obstetrics and Gynecology, Oregon Health & Science University, Portland, Oregon, USA.
Rose BenderYale University School of Medicine, New Haven, Connecticut, USA.
Jennifer DavilaChildren's Hospital at Montefiore and Albert Einstein College of Medicine, Bronx, NY, USA.
Brendan HayesNational Bleeding Disorders Foundation, New York, NY, USA.
Amanda Jacobson-KellyNationwide Children's Hospital, The Ohio State University College of Medicine, Columbus, Ohio, USA.
Peter KouidesMary M. Gooley Hemophilia Treatment Center, Rochester, NY, USA.
Michele P LambertChildren's Hospital of Philadelphia and Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Shilpa NatarajDepartment of Pediatrics, Stanford University, Palo Alto, California, USA.
Michelle SholzbergSt. Michael's Hospital, Li Ka Shing Knowledge Institute, University of Toronto, Toronto, Ontario, Canada.
Roona SinhaRoyal University Hospital, Division of Pediatric Hematology-Oncology, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.
Hanny Al-SamkariMassachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA.
Amy L DunnNationwide Children's Hospital, The Ohio State University College of Medicine, Columbus, Ohio, USA.

Funding

National Bleeding Disorder Foundation
6 · The paper itself

Abstract

introductionThe National Bleeding Disorder Foundation (NBDF) Medical and Scientific Advisory Council (MASAC) was formed in 1954 and issues recommendations and advisories pertinent to the bleeding disorders community. MASAC is comprised of > 25 rotating members from different medical disciplines and lived experience experts.

aimThe Iron Deficiency Taskforce was formed to address the concern for undertreatment and misdiagnosis of iron deficiency with and without anemia in the inherited bleeding disorder community. Members included MASAC members and individuals outside of MASAC with clinical, research, and lived experience expertise and/or interest in iron deficiency and screening in the bleeding disorders community. Currently, there are no published standardized approaches, guidelines, or recommendations that address iron deficiency screening for a population of individuals at high risk of experiencing iron deficiency and its associated complications

methodDue to the limited published peer-reviewed data on the prevalence of iron deficiency and anemia in this population, this document was devised by consensus recommendations amongst members of the Iron Deficiency Taskforce with additional review and feedback from all MASAC members.

resultThis document identifies individuals within the inherited bleeding disorder population at risk for iron deficiency with and without anemia providing consensus recommendations on indications for screening, approach to screening, and general management considerations if iron deficiency and anemia are identified. Recommendations for higher hemoglobin (< 13 g/dL) and ferritin (< 50 ng/mL) thresholds for anemia and iron deficiency diagnoses, respectively, are also discussed.

conclusionFurther research is necessary to understand the impact of iron deficiency in inherited bleeding disorders.

Indexed as

Anemia, Iron-DeficiencyBlood Coagulation Disorders, InheritedHemorrhagic DisordersIron DeficienciesMass ScreeningFemaleHumansanemfiableedingheavy menstrual bleedinginherited bleeding disordersiron deficiencypregnancy

Identifiers

PMID41801990
PMCPMC13175440

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.