Evidence map›Paper›PMID 41801888›Full record

ArticlePloS one2026

Suicidal ideation and interrelated psychiatric disturbances in rheumatoid arthritis: Evidence from a Vietnamese cohort.

Ha Thi Thu Tran, Tam Minh Duong, Tuan Van Nguyen, Ha Thi Thu Le, Hue Thi Doan, Yen Hoang Nguyen, Hoa Thi Nguyen, Long Thanh Nguyen, Thang Xuan Pham, An Thi Ha Tran and 4 more

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Article in PloS one, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

14 authors.

Ha Thi Thu TranDepartment of Psychiatry, Hanoi Medical University, Hanoi, Vietnam.ORCID https://orcid.org/0000-0003-3064-0984
Tam Minh DuongDepartment of Psychiatry, Hanoi Medical University, Hanoi, Vietnam.
Tuan Van NguyenDepartment of Psychiatry, Hanoi Medical University, Hanoi, Vietnam.
Ha Thi Thu LeDepartment of Psychiatry, Hanoi Medical University, Hanoi, Vietnam.
Hue Thi DoanDepartment of Psychiatry, Hanoi Medical University, Hanoi, Vietnam.
Yen Hoang NguyenDepartment of Psychiatry, Hanoi Medical University, Hanoi, Vietnam.ORCID https://orcid.org/0000-0001-8880-8722
Hoa Thi NguyenDepartment of Psychiatry, Hanoi Medical University, Hanoi, Vietnam.ORCID https://orcid.org/0000-0002-3481-2248
Long Thanh NguyenDepartment of Psychiatry, Hanoi Medical University, Hanoi, Vietnam.
Thang Xuan PhamDepartment of Psychiatry, Hanoi Medical University, Hanoi, Vietnam.ORCID https://orcid.org/0000-0003-0959-1444
An Thi Ha TranDepartment of Psychiatry, Hanoi Medical University, Hanoi, Vietnam.
Phi Van NguyenDepartment of Psychiatry, Hanoi Medical University, Hanoi, Vietnam.
Son Truong HoangDepartment of Psychiatry, Hanoi Medical University, Hanoi, Vietnam.
Thien Cong LeDepartment of Psychiatry, Hanoi Medical University, Hanoi, Vietnam.
Hung Van NguyenRheumatology Center, Bach Mai Hospital, Hanoi, Vietnam.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study aimed to determine the prevalence of suicidal ideation among Vietnamese patients with rheumatoid arthritis (RA), and to examine associated factors, other psychiatric disturbances, and quality of life (QoL).

methodsA cross-sectional study was conducted from June 2024 to December 2024 at Bach Mai Hospital, Hanoi. Eligible patients met the 1987 ACR classification criteria for RA. Suicidal ideation was assessed through structured psychiatric interviews. Depression, anxiety, insomnia, and sexual dysfunction were evaluated using the PHQ-9, HAM-A, ISI, and ASEX, respectively, while QoL was measured with the EQ-5D-5L. Correlation analyses and structural equation modeling (SEM) explored interrelationships among psychiatric disturbances. Multivariable regression was applied to identify predictors of suicidal ideation, psychiatric symptoms, and QoL.

resultsAmong 187 participants (mean age 56.9 ± 12.7 years; 84.0% female), 13.4% reported suicidal ideation. Anxious (45.5%), insomnia (48.1%) and depressive symptoms (28.3%) were highly common, and depressive, anxiety, and insomnia symptoms were strongly interrelated (e.g., r = 0.74-0.80). The mean EQ-5D-5L index value was 0.6 ± 0.2, indicating moderate impairment in overall QoL. SEM confirmed high correlation between psychiatric (DEP, ANX) and behavioral (SLP, SEX) disturbances. Multivariable analysis showed that high disease activity, joint deformity, and treatment-related adverse effects were consistently associated with suicidal ideation, psychiatric symptoms, and impaired QoL.

conclusionSuicidal ideation and other psychiatric disturbances are commonly observedamong patients with RA in Vietnam. Disease activity, structural damage, and medication-related adverse effects were major determinants, underscoring the need for integrated mental health screening and multidisciplinary management to optimize both clinical and psychosocial outcomes.

Indexed as

Arthritis, RheumatoidSuicidal IdeationAdultAgedAnxietyCross-Sectional StudiesDepressionFemaleHumansMaleMiddle AgedPrevalenceQuality of LifeVietnam

Identifiers

PMID41801888
PMCPMC12970863

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