Evidence map›Paper›PMID 41801665›Full record

ArticleOphthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists)2026

Influence of Light Wavelength and Optotype Size on Accommodative Response and Aberrometric Changes Across the Adult Lifespan.

Inés Cabrera-Guardiola, Elvira Orduna-Hospital, María Arcas-Carbonell, Ana Sanchez-Cano

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Article in Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Inés Cabrera-GuardiolaDepartment of Applied Physics, University of Zaragoza, Zaragoza, Spain.ORCID http://orcid.org/0009-0005-9825-1960
Elvira Orduna-HospitalDepartment of Applied Physics, University of Zaragoza, Zaragoza, Spain. eordunahospital@unizar.es.ORCID http://orcid.org/0000-0003-2710-1875
María Arcas-CarbonellDepartment of Applied Physics, University of Zaragoza, Zaragoza, Spain.ORCID http://orcid.org/0009-0006-7694-8086
Ana Sanchez-CanoDepartment of Applied Physics, University of Zaragoza, Zaragoza, Spain.ORCID http://orcid.org/0000-0002-5621-1937

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo analyse the effects of chromatic light (white, blue, red and green) and stimulus size (6/6 and 6/12) on pupil constriction, Zernike coefficients and the accommodative response curve using wavefront aberrometry across a wide age range of healthy subjects.

methodsOne hundred and sixty-four right eyes from participants aged 20-75 years were evaluated. All subjects showed normal near visual function for their age. Wavefront aberrations were measured under scotopic conditions using the IRX3 aberrometer. Accommodation was induced from 0 to 10 D in the younger group and from 0 to 5 D in the full sample. Stimuli varied in colour and size. Pupil diameter and Zernike coefficients were analysed, rescaling all maps to a 3.00 and a 3.65 mm pupil, respectively.

resultsMean pupil diameter ± standard deviation decreased progressively with increasing accommodative demand by 0.51 ± 0.06 mm in the full sample (0-5 D) and by 2.09 ± 0.11 mm in the younger group (0-10 D). The greatest changes were observed under white light and larger stimuli. The Zernike component C(2,0) varied significantly across all filters, optotype sizes and in both the total (p < 0.003) and the younger (p < 0.0009) groups. However, C(4,0) showed significant changes in all conditions for the younger group (p < 0.0009), particularly at higher demands. An initial overaccommodation of approximately 1 D at baseline was followed by a progressive lag beyond 5 D, being more pronounced under red light, where the accommodative response was lowest, while white light consistently elicited the strongest response. Larger stimuli induced greater responses than smaller ones, especially at high demands.

conclusionAccommodation efficiency varies with wavelength and stimulus size: white and blue lights triggered greater pupil constriction and accommodation than red and green, with corresponding changes in defocus and spherical aberration. Small stimuli improved low-demand responses, while larger ones were more effective at higher demands.

Indexed as

Accommodation, OcularAgingLightPupilAberrometryAdultAgedFemaleHumansMaleMiddle AgedPhotic StimulationYoung AdultAge-related accommodation responseChromatic stimuliPupil diameterTarget sizeWavefront aberrometryZernike coefficients

Identifiers

PMID41801665
PMCPMC13369024

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.