Evidence map›Paper›PMID 41801584›Full record

ArticleJournal of robotic surgery2026

Robot-assisted versus open surgery for multiple ipsilateral renal tumors: a multicenter matched cohort study (UroCCR-60).

Gaëlle Margue, Candice Debard, Clément Klein, Nicolas Doumerc, Karim Bensalah, Charles Dariane, Franck Bruyere, Jérome Rizk, Cédric Lebacle, Pierre Bigot and 5 more

Registry-linked trialAbstract readMulticenter StudyComparative Study
PubMed Publisher
In one paragraph

Article in Journal of robotic surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03293563 (UroCCR Database), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03293563 recruitingnot on this map

UroCCR Database: French Research Network for Kidney Cancer (National Multidisciplinary Clinical and Biological Database on Kidney Cancer)

TypeobservationalSponsorUniversity Hospital, BordeauxRan2011 to 2040Enrolled30,000ConditionsKidney CancerArmsRadical nephrectomy versus partial nephrectomy (according surgeon judgement)
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Gaëlle MargueBordeaux University Hospital, Urology, France. gaelle.margue@chu-bordeaux.fr.ORCID http://orcid.org/0000-0001-5311-1597
Candice DebardBordeaux University Hospital, Urology, France.
Clément KleinBordeaux University Hospital, Urology, France.
Nicolas DoumercFrench AFU Cancer Committee Guidelines, Paris, France.
Karim BensalahRennes University Hospital, Urology, France.
Charles DarianeFrench AFU Cancer Committee Guidelines, Paris, France.
Franck BruyereTours University Hospital, Urology, France.
Jérome RizkHP La Louvière, Lille, Urology, France.
Cédric LebacleKremlin Bicêtre, Paris, Urology, France.
Pierre BigotFrench AFU Cancer Committee Guidelines, Paris, France.
Alexandre De la TailleHenri Mondor, Paris, Urology, France.
Hervé LangStrasbourg University Hospital, Urology, France.
Arnaud MejeanHEGP, Paris, Urology, France.
Morgan RoupretFrench AFU Cancer Committee Guidelines, Paris, France.
Jean-Christophe BernhardBordeaux University Hospital, Urology, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Patients with multiple ipsilateral renal tumors face an increased risk of recurrence, making nephron-sparing surgery (NSS) essential to preserve renal function. Due to their technical complexity, these procedures have traditionally been performed via open partial nephrectomy (OPN). This study aimed to compare perioperative, functional, and oncologic outcomes of robot-assisted partial nephrectomy (RAPN) versus OPN in this challenging setting. We conducted a retrospective analysis of prospectively collected data from 20 centers of the French national kidney cancer research network UroCCR (NCT03293563; CNIL DR-2022-091). The primary endpoint was perioperative morbidity, assessed using the Clavien–Dindo classification. Secondary outcomes included Trifecta achievement, renal functional outcomes (pre- and 3-month postoperative eGFR, new-onset CKD, and AKI), and oncologic outcomes (disease-free survival [DFS], and overall survival [OS]). Overall, 212 patients underwent NSS for multiple ipsilateral renal tumors between June 2007 and July 2025 (146 RAPN, 66 OPN). After 1:1 matching for BMI, ASA score, and indication for NSS, 132 patients were analyzed (66 per group). RAPN was associated with shorter hospitalization (3.2 vs. 7.7 days, p < 0.001), fewer complications (6.1% vs. 21.2%, p = 0.02), and less frequent main renal artery clamping (51.5% vs. 86.4%, p < 0.001), despite longer operative and clamping times. Trifecta rates (50.8% vs. 61.9%, p = 0.29) and renal function at 3 months were comparable. At a median follow-up of 30.7 months, DFS and OS did not differ significantly between groups (p = 0.69). RAPN is a safe and effective alternative to OPN for multiple ipsilateral renal tumors, providing comparable oncologic and functional outcomes with reduced morbidity.

Indexed as

Kidney NeoplasmsNephrectomyOrgan Sparing TreatmentsRobotic Surgical ProceduresAgedCohort StudiesFemaleHumansLength of StayMaleMiddle AgedRetrospective StudiesTreatment OutcomeMultiple renal tumorsNephron-sparing surgeryOpen partial nephrectomyRenal cell carcinomaRobot-assisted partial nephrectomy

Identifiers

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.