Evidence map›Paper›PMID 41801532›Full record

Trial reportClinical oral investigations2026

Transfer accuracy of three different virtually designed CAD/CAM retainers - baseline results of a randomized clinical trial.

Felix Linnerz, Rana Victoria Aghamiri, Inas Ayad, Mette Kuijpers, Jan Willem Hoekstra, Sachin Chhatwani, Gholamreza Danesh, Stephan Christian Möhlhenrich

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Clinical oral investigations, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Felix LinnerzDepartment of Orthodontics, Witten/Herdecke University, Alfred-Herrhausen Str. 45, 58455, Witten, Germany.
Rana Victoria AghamiriDepartment of Orthodontics, Witten/Herdecke University, Alfred-Herrhausen Str. 45, 58455, Witten, Germany.
Inas AyadDepartment of Orthodontics, Witten/Herdecke University, Alfred-Herrhausen Str. 45, 58455, Witten, Germany.
Mette KuijpersDepartment of Dentistry, Section of Orthodontics, Dentofacial Orthopedics and Craniofacial Biology, Radboud University Medical Centre, THK 309, P.O. Box 9101, Nijmegen, 6500 HB, The Netherlands.
Jan Willem HoekstraDepartment of Dentistry, Section of Orthodontics, Dentofacial Orthopedics and Craniofacial Biology, Radboud University Medical Centre, THK 309, P.O. Box 9101, Nijmegen, 6500 HB, The Netherlands.
Sachin ChhatwaniDepartment of Orthodontics, Witten/Herdecke University, Alfred-Herrhausen Str. 45, 58455, Witten, Germany.
Gholamreza DaneshDepartment of Orthodontics, Witten/Herdecke University, Alfred-Herrhausen Str. 45, 58455, Witten, Germany.
Stephan Christian MöhlhenrichDepartment of Orthodontics, Witten/Herdecke University, Alfred-Herrhausen Str. 45, 58455, Witten, Germany. stephan.moehlhenrich@radboudumc.nl.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThis study aimed to evaluate the immediate three-dimensional (3D) transfer accuracy of three virtually designed CAD/CAM lingual retainers fabricated from nickel–titanium (NiTi), titanium grade 5 (Ti5), and cobalt–chromium (CoCr). The investigation represents the baseline (T = 0) phase of a registered randomized clinical trial (DRKS00028974). MATERIALS AND

methodsSixty patients (32 females, 28 males; mean age 19.2 ± 6.9 years) were randomly allocated to receive one of the three CAD/CAM retainers. Immediately after bonding (T0–T1), intraoral scans were superimposed with the digital design to determine deviations at predefined interproximal contact points. Non-parametric Kruskal–Wallis tests with Dunn’s post-hoc comparisons were applied (p ≤ 0.05).

resultsAll 60 patients completed the baseline assessment. Transfer deviations were lowest in the NiTi group (0.17 mm, IQR 0.16–0.21), followed by Ti5 (0.37 mm, IQR 0.32–0.41) and CoCr (0.35 mm, IQR 0.30–0.40). NiTi showed significantly higher transfer accuracy compared with Ti5 (p < 0.001) and CoCr (p < 0.001). No significant difference was observed between Ti5 and CoCr (p > 0.999). No adverse events occurred.

conclusionsLaser-cut NiTi CAD/CAM retainers demonstrated significantly higher immediate transfer precision than milled Ti5 and CoCr retainers. These findings represent the baseline phase of the ongoing randomized clinical trial; subsequent analyses will determine whether such accuracy differences translate into clinically relevant stability outcomes. CLINICAL RELEVANCE: Accurate passive fit of CAD/CAM retainers is essential to prevent unwanted forces on teeth. Understanding material-dependent transfer deviations may improve digital bonding workflows and guide material selection in clinical orthodontics.

trial registrationDRKS00028974 (registered May 2022)

Indexed as

Computer-Aided DesignOrthodontic Appliance DesignOrthodontic RetainersAdolescentDental AlloysFemaleHumansMaleTitaniumYoung AdultDental AlloysTitaniumCobalt–chromiumComputer-aided designLingual retentionNickel–titaniumOrthodontic retainersTransfer accuracy

Identifiers

PMID41801532
PMCPMC12971807

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.