Evidence map›Paper›PMID 41801514›Full record

Trial reportClinical oral investigations2026

Prospective, randomized, paired-comparison clinical trial of a new universal adhesive in posterior composite restorations: A 2-year evaluation.

Jorge Perdigão, Kelli A Trauger, Carla I Campbell, Hooi Pin Chew, Ignatius K Lee, Kacie Woodis

Abstract readRandomized Controlled TrialComparative Study
In one paragraph

Trial report in Clinical oral investigations, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jorge PerdigãoDepartment of Restorative Sciences, Division of Operative Dentistry, University of Minnesota School of Dentistry, Minneapolis, MN, 55455, USA. perdi001@umn.edu.
Kelli A TraugerOral Health Clinical Research Center, University of Minnesota School of Dentistry, Minneapolis, MN, 55455, USA.
Carla I CampbellOral Health Clinical Research Center, University of Minnesota School of Dentistry, Minneapolis, MN, 55455, USA.
Hooi Pin ChewDepartment of Restorative Sciences, Division of Operative Dentistry, University of Minnesota School of Dentistry, Minneapolis, MN, 55455, USA.
Ignatius K LeeDepartment of Restorative Sciences, Division of Operative Dentistry, University of Minnesota School of Dentistry, Minneapolis, MN, 55455, USA.
Kacie WoodisDepartment of Primary Dental Care, Division of Comprehensive Care, University of Minnesota School of Dentistry, Minneapolis, MN, 55455, USA.

Funding

University of Minnesota Clinical and Translational Science Institute (UMN CTSI)UM1TR004405 · NCATS · UNIVERSITY OF MINNESOTA · PI Bruce R Blazar, Damien A Fair · 2023 to 2026
$30.8M
NCATS NIH HHS UM1 TR004405
6 · The paper itself

Abstract

objectiveThis prospective, randomized, post-market, paired-comparison controlled trial compared the 2-year clinical performance of a new universal adhesive, Scotchbond Universal Plus Adhesive (SBU+), with that of Scotchbond Universal Adhesive (SBU). Both were applied as self-etch (SE) adhesives for composite resin restoration of Class I and Class II preparations. MATERIALS AND

methodsTwo posterior teeth in each of 51 subjects were randomized in a 1:1 ratio to a restoration with SBU + or to a restoration with SBU (control) applied with the SE strategy. Class I and/or Class II preparations were restored with Filtek Universal Restorative. Two calibrated and blinded examiners evaluated the restorations at baseline, 6 months, 1 year, and 2 years, using the modified FDI criteria. The Wilcoxon signed-rank test was used to compare the outcomes.

resultsAt the 2-year evaluation, retention was 100% for both the SBU + and SBU groups. Regarding fracture and retention, 36 of the 37 SBU+ restorations (97%) were graded “Clinically Excellent/Very Good,” while 1/37 (3%) was graded “Clinically Satisfactory.” All 38 SBU restorations (100%) were graded “Clinically Excellent/Very Good”. Marginal adaptation was clinically acceptable for all restorations at 2 years, with no statistically significant difference between the two adhesive materials. Furthermore, no recurrent caries lesions were observed at 2 years, and no restorations received a “Clinically Insufficient/Unsatisfactory” or “Clinically Poor” grade for any FDI criteria during any evaluation visit.

conclusionsAt 2 years, SBU+ exhibited clinical efficacy similar to its predecessor, SBU, in Class I and Class II restorations in adult patients when using the self-etch (SE) technique. CLINICAL RELEVANCE: Mildly acidic universal dental adhesives may be used for posterior composite restorations without prior phosphoric acid etching.

Indexed as

Composite ResinsDental CementsDental Restoration, PermanentResin CementsAdultDentin-Bonding AgentsFemaleHumansMaleMiddle AgedProspective StudiesComposite ResinsDental CementsDentin-Bonding AgentsResin CementsScotchbondclinical studyclinical trialdental adhesionDental bonding

Identifiers

PMID41801514
PMCPMC12971827

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.