Evidence map›Paper›PMID 41801349›Full record

ArticleEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2026

Medical outcomes after canal wall-down mastoidectomy, external ear canal reconstruction, tympanoplasty, and mastoid obliteration for extensive cholesteatoma.

Michal Luntz, Keren Hod, Roni Barzilai

Abstract read
In one paragraph

Article in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Michal LuntzThe Israel Society for Auditory Research, Tel Aviv, Israel.
Keren HodDepartment of Nutritional Sciences, School of Health Sciences, Ariel University, Ariel, Israel.
Roni BarzilaiTechnion Israel Institute of Technology, The Ruth and Bruce Rappaport Faculty of Medicine, Haifa, Israel. Ronibarzilay1@gmail.com.ORCID http://orcid.org/0000-0002-7027-4221

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo report medical outcomes and time-related recidivism after extensive cholesteatoma treated with canal wall-down (CWD) mastoidectomy, external ear canal (EEC) reconstruction, tympanoplasty, and S53P4 bioactive-glass mastoid obliteration.

methodsRetrospective study of 127 ears with extensive cholesteatoma treated at a tertiary center. Patients were scheduled for annual otoscopic and non-echo-planar DW MRI follow-up for up to 4 years. For each postoperative year, only ears attending that visit and all previous yearly visits were analyzed. Main outcomes were: completely epithelialized, dry ear; tympanic membrane and/or posterior–superior EEC retraction; retraction pocket (RP) cholesteatoma; and residual cholesteatoma on MRI.

resultsFollow-up attendance declined from 100% (127/127) in year 1 to 67.2% (41/61) in year 4. A dry, epithelialized ear was achieved in 96.9% (123/127). Retraction developed in 33.9% (43/127), with probabilities of 13.4%, 26.4%, 28.9%, and 34.1% at 1, 2, 3, and 4 years, respectively. RP cholesteatoma occurred in 11.8% (15/127) and residual cholesteatoma on MRI in 7.0% (9/127); 23% of retracted ears progressed to RP cholesteatoma. Children ≤ 11 years had higher rates of retraction and RP cholesteatoma.

conclusionsDespite counseling on the importance of follow-up, attendance declined over time. CWD mastoidectomy with EEC reconstruction, tympanoplasty, and S53P4 obliteration yielded high long-term dry ear rates in extensive and recurrent cholesteatoma, but complete eradication was not achieved. Younger and re-operated patients were at higher risk of retraction and RP cholesteatoma. Recidivism appeared years after the first surgery, supporting prolonged follow-up. Reporting annual outcome incidence in future studies would enhance understanding of extensive cholesteatoma.

Indexed as

Cholesteatoma, Middle EarEar CanalMastoidMastoidectomyPlastic Surgery ProceduresTympanoplastyAdolescentAdultAgedChildFemaleFollow-Up StudiesHumansMagnetic Resonance ImagingMaleMiddle AgedBioactive glassCanal wall-down mastoidectomyCholesteatomaMastoid obliterationTympanoplasty

Identifiers

PMID41801349
PMCPMC13152934

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.