Evidence map›Paper›PMID 41801185›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2026

Light-Harvesting Photothermal Hotspots Enabled by NIR Scattering-Absorption Coupling.

Zebin Wu, Changming Bao, Pengyu Zhang, Tao Ding, Weiming Lin, Haodong Li, Wenjian Luo, Xizhi Deng, Hao Wang, Guanle Li and 8 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Zebin WuThe Institute for Advanced Studies (IAS), Department of Ophthalmology, Zhongnan Hospital of Wuhan University, State Key Laboratory of Metabolism and Regulation in Complex Organisms, College of Life Sciences, Wuhan University, Wuhan, China.
Changming BaoThe Institute for Advanced Studies (IAS), Department of Ophthalmology, Zhongnan Hospital of Wuhan University, State Key Laboratory of Metabolism and Regulation in Complex Organisms, College of Life Sciences, Wuhan University, Wuhan, China.
Pengyu ZhangDepartment of Ophthalmology, Zhongnan Hospital of Wuhan University, Wuhan, China.
Tao DingThe Institute for Advanced Studies (IAS), Department of Ophthalmology, Zhongnan Hospital of Wuhan University, State Key Laboratory of Metabolism and Regulation in Complex Organisms, College of Life Sciences, Wuhan University, Wuhan, China.
Weiming LinThe Institute for Advanced Studies (IAS), Department of Ophthalmology, Zhongnan Hospital of Wuhan University, State Key Laboratory of Metabolism and Regulation in Complex Organisms, College of Life Sciences, Wuhan University, Wuhan, China.
Haodong LiThe Institute for Advanced Studies (IAS), Department of Ophthalmology, Zhongnan Hospital of Wuhan University, State Key Laboratory of Metabolism and Regulation in Complex Organisms, College of Life Sciences, Wuhan University, Wuhan, China.
Wenjian LuoThe Institute for Advanced Studies (IAS), Department of Ophthalmology, Zhongnan Hospital of Wuhan University, State Key Laboratory of Metabolism and Regulation in Complex Organisms, College of Life Sciences, Wuhan University, Wuhan, China.
Xizhi DengThe Institute for Advanced Studies (IAS), Department of Ophthalmology, Zhongnan Hospital of Wuhan University, State Key Laboratory of Metabolism and Regulation in Complex Organisms, College of Life Sciences, Wuhan University, Wuhan, China.
Hao WangDepartment of Nuclear Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Guanle LiDepartment of Ophthalmology, Zhongnan Hospital of Wuhan University, Wuhan, China.
Hongyue HuThe Institute for Advanced Studies (IAS), Department of Ophthalmology, Zhongnan Hospital of Wuhan University, State Key Laboratory of Metabolism and Regulation in Complex Organisms, College of Life Sciences, Wuhan University, Wuhan, China.
Ye WangThe Institute for Advanced Studies (IAS), Department of Ophthalmology, Zhongnan Hospital of Wuhan University, State Key Laboratory of Metabolism and Regulation in Complex Organisms, College of Life Sciences, Wuhan University, Wuhan, China.
Dawei JiangDepartment of Nuclear Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Yu ZhangThe Interdisciplinary Research Center, Shanghai Synchrotron Radiation Facility, Zhangjiang Laboratory, Shanghai Advanced Research Institute, Chinese Academy of Sciences, Shanghai, China.
Sisi JiaZhangjiang Laboratory, Shanghai, China.
Nan ZhangDepartment of Ophthalmology, Zhongnan Hospital of Wuhan University, Wuhan, China.
Min KeDepartment of Ophthalmology, Zhongnan Hospital of Wuhan University, Wuhan, China.
Le LiangThe Institute for Advanced Studies (IAS), Department of Ophthalmology, Zhongnan Hospital of Wuhan University, State Key Laboratory of Metabolism and Regulation in Complex Organisms, College of Life Sciences, Wuhan University, Wuhan, China.ORCID https://orcid.org/0009-0002-9484-5057

Funding

Fundamental Research Funds for the Central UniversitiesNational Natural Science Foundation of China 22374112National Natural Science Foundation of China 82571215Start-Up Fund of Wuhan UniversityTranslational Medicine and Interdisciplinary Research Joint Fund of Zhongnan Hospital of Wuhan University ZNJC202216
6 · The paper itself

Abstract

Efficient near-infrared (NIR) photothermal conversion is constrained by photon loss from scattering and attenuation in complex media. We present a scattering-absorption coupling strategy that pairs broadband photon scattering with plasmonic absorption to deliver supra-additive heating. Nanodiamonds (ND) multiply scatter and trap NIR photons, elevating local photon density, while neighboring gold nanostars (AuNS) convert the enriched flux into heat with high efficiency. A multi-scale framework links mechanism to outcome: finite-difference time-domain calculations quantify AuNS absorbed-power gains in the proximity of ND, and Monte Carlo photon transport yields a depth-dependent photon-density enhancement that together predicts the measured temperature rises. In agarose phantoms and bacterial plates, ND increases NIR absorption and, when combined with AuNS, produces greater-than-additive heating. In cells, endogenous endocytosis brings ND and AuNS into lysosomal microenvironments that act as confined "hotspots" enabling low-power ablation; the power density required for 50% cell kill (LD

Indexed as

GoldMetal NanoparticlesPhotothermal TherapyAnimalsHumansInfrared RaysMiceGoldendocytosis‐driven hotspotsgold nanostarslow‐power photothermal ablationnanodiamondsphotothermal conversionscattering–absorption coupling

Identifiers

PMID41801185
PMCPMC13170250

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.