Evidence map›Paper›PMID 41800661›Full record

ArticleOtolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery2026

Migraine Features in Patients With Sudden Sensorineural Hearing Loss.

Yalda Yazdani, Ella J Lee, Amanda Francis, Saharnaz Nedjat, Mehdi Abouzari, Hamid R Djalilian

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Article in Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Yalda YazdaniDepartment of Otolaryngology-Head and Neck Surgery, University of California, Irvine, USA.
Ella J LeeDepartment of Otolaryngology-Head and Neck Surgery, University of California, Irvine, USA.
Amanda FrancisDepartment of Otolaryngology-Head and Neck Surgery, University of California, Irvine, USA.
Saharnaz NedjatDepartment of Otolaryngology-Head and Neck Surgery, University of California, Irvine, USA.
Mehdi AbouzariDepartment of Otolaryngology-Head and Neck Surgery, University of California, Irvine, USA.ORCID https://orcid.org/0000-0002-3585-698X
Hamid R DjalilianDepartment of Otolaryngology-Head and Neck Surgery, University of California, Irvine, USA.ORCID https://orcid.org/0000-0001-5905-0270

Funding

University of California Health Participation in the National COVID Cohort Collaborative (N3C)UL1TR001414 · NCATS · UNIVERSITY OF CALIFORNIA-IRVINE · PI COOPER, DAN M, VILAIN, ERIC J. · 2015 to 2023
$35.1M
NRSA Training CoreTL1TR001415 · NCATS · UNIVERSITY OF CALIFORNIA-IRVINE · PI CAIOZZO, VINCENT JAMES, HEAD, ELIZABETH · 2015 to 2023
$4.2M
NCATS NIH HHS TL1TR001415NCATS NIH HHS UL1 TR001414NCRR NIH HHS TL1TR001415
6 · The paper itself

Abstract

objectiveTo investigate the prevalence of migraine features among patients with sudden sensorineural hearing loss (SSNHL) and evaluate potential clinical associations. STUDY

designRetrospective survey-based study.

settingSingle institution tertiary care center.

methods168 adult patients with SSNHL were recruited. Migraine diagnosis was determined using International Classification of Headache Disorders, 3rd edition (ICHD-3) criteria. Patient demographics, migraine-related features, and SSNHL characteristics were analyzed using univariate and multivariate logistic regression.

resultsOf 168 SSNHL patients, 77 (46%) met full ICHD-3 migraine criteria, which is higher than the general population. An additional 23% met the majority of the migraine criteria. Multivariate analysis revealed that aural fullness preceding hearing loss (P < .001), concordant laterality of hearing loss and headache (P < .001), hyperacusis (P = .006), otalgia (P = .01), and motion sickness (P = .03) were independently associated with migraine. Interestingly, 89% of patients with migraine headache and SSNHL had their SSNHL on the same side as their headaches.

conclusionsThese findings reveal a high prevalence of migraine headache among patients with SSNHL. Clinical features, including aural fullness and concordant laterality (dominant headaches on the same side as SSNHL), were predictive of migraine in SSNHL patients. These findings support the hypothesis that migraine and SSNHL may share overlapping vascular and neurogenic mechanisms, highlighting the importance of identifying migraine features in SSNHL to optimize management and explore potential therapeutic strategies.

Indexed as

Hearing Loss, SensorineuralHearing Loss, SuddenMigraine DisordersAdultAgedFemaleHumansMaleMiddle AgedPrevalenceRetrospective Studiescochlear migraineheadachemigrainesudden sensorineural hearing loss

Identifiers

PMID41800661
PMCPMC13126431

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.