ArticleCell transplantation
Gelatin sponge loaded with hypoxic human umbilical cord mesenchymal stem cell exosomes promotes healing of enterocutaneous fistula.
Article in Cell transplantation. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Application of Human Umbilical Cord Mesenchymal Stem Cells and Their Derived Exosomes in Gastrointestinal Diseases.International journal of nanomedicine · 2026Review
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Authors and funding
4 authors.
Funding
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Abstract
Enterocutaneous fistula (ECF) traditionally relies on surgical treatment and lacks effective therapies to promote tissue regeneration. This study constructed a composite system based on hypoxia-preconditioned human umbilical cord mesenchymal stem cell-derived exosomes loaded onto a gelatin sponge (GS Hypo-Exos), aiming to explore its potential application in ECF treatment. First, systematic characterization of exosomes was performed: transmission electron microscopy, nanoparticle tracking analysis, western blot, and flow cytometry confirmed successful exosome extraction. Material evaluation indicated that the gelatin sponge exhibited high porosity and good biocompatibility. Scanning electron microscopy confirmed successful loading of exosomes onto the sponge surface, and
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