Evidence map›Paper›PMID 41800513›Full record

ArticleThe Canadian journal of urology2026

Prolonged survival and risk factors for reintervention after inflatable penile prosthesis implantation.

Skander Zouari, Flora Barthe, Arnoult Morrone, Lionel Mendel, Imad Bentellis, Louis Vignot, Romain Haider, Younes Ahallal, Daniel Chevallier, Matthieu Durand

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Article in The Canadian journal of urology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Skander ZouariDepartment of Urology, Andrology, and Kidney Transplantation, Pasteur 2 Hospital, University Hospital of Nice, Nice, 06000, France.
Flora BartheDepartment of Urology, Andrology, and Kidney Transplantation, Pasteur 2 Hospital, University Hospital of Nice, Nice, 06000, France.
Arnoult MorroneDepartment of Urology, Andrology, and Kidney Transplantation, Pasteur 2 Hospital, University Hospital of Nice, Nice, 06000, France.
Lionel MendelClinique Saint-Jean, Cagnes-Sur-Mer, 06800, France.
Imad BentellisClinique Saint-Jean, Cagnes-Sur-Mer, 06800, France.
Louis VignotDepartment of Urology, Andrology, and Kidney Transplantation, Pasteur 2 Hospital, University Hospital of Nice, Nice, 06000, France.
Romain HaiderDepartment of Urology, Andrology, and Kidney Transplantation, Pasteur 2 Hospital, University Hospital of Nice, Nice, 06000, France.
Younes AhallalDepartment of Urology, Andrology, and Kidney Transplantation, Pasteur 2 Hospital, University Hospital of Nice, Nice, 06000, France.
Daniel ChevallierDepartment of Urology, Andrology, and Kidney Transplantation, Pasteur 2 Hospital, University Hospital of Nice, Nice, 06000, France.
Matthieu DurandDepartment of Urology, Andrology, and Kidney Transplantation, Pasteur 2 Hospital, University Hospital of Nice, Nice, 06000, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundInflatable Penile Prosthesis (IPP) is the treatment for erectile dysfunction (ED) refractory to pharmacological therapies. Long-term data on factors associated with prosthesis survival remain unclear. This study aimed to analyze the long-term survival of penile prostheses and identify risk factors associated with survival without reintervention.

methodsThis is a retrospective, single-center study of patients who underwent IPP implantation between January 2014 and December 2022. Preoperative data related to the patient and the etiology of ED, as well as perioperative data, were collected. The primary outcome was survival without reintervention, defined as prosthesis revision or explantation due to mechanical dysfunction or infection. We conducted survival analyses without reintervention and searched for risk factors using a multivariate Cox model.

resultsIn total, 33 out of 137 patients underwent reintervention (24.1%), including 24 (17.5%) prosthesis revisions and 9 (6.6%) had explantations. Median follow-up was 39 months with an interquartile range (IQR) of 9.00 to 62.00. Median survival without reintervention was 7 years. In univariate analysis, downsizing (p = 0.046) was associated with reintervention. Smoking (p = 0.003) and age (p = 0.034) were associated with prosthesis explantation. The number of implantations (p = 0.009) was associated with prosthesis revision. Multivariate analysis by the Cox model did not identify any independent predictive factors for reintervention.

conclusionSmoking may play a role in infection post-IPP implantation. Primary implantations seem to be associated with better survival. Adjusting cylinder size, known as downsizing, is likely to be a proxy for the complexity of the procedure and thus linked to earlier reintervention.

Indexed as

Erectile DysfunctionPenile ImplantationPenile ProsthesisProsthesis FailureReoperationAgedDevice RemovalHumansMaleMiddle AgedProsthesis DesignRetrospective StudiesRisk FactorsTime Factorserectile dysfunctionimplant survivalinflatable penile prosthesislong-term follow-upmechanical dysfunctionsurgical reoperation

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.