ArticleMaterials today. Bio2026
A precise theranostic nanoplatform amplifies anti-tumor efficacy via copper ionophores and sonodynamic therapy.
Article in Materials today. Bio, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Copper homeostasis and cuproptosis rewire the tumor microenvironment: mechanisms, immune modulation, and therapeutic opportunities.Journal of hematology & oncology · 2026Review
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Authors and funding
6 authors.
Funding
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Abstract
Tumor heterogeneity and therapeutic resistance remain major challenges in cancer treatment. Sonodynamic therapy (SDT), a noninvasive therapeutic modality with deep tissue penetration capability, has shown considerable promise in tumor therapy. However, its efficacy is often limited by insufficient reactive oxygen species (ROS) generation and the lack of real-time treatment monitoring. Cuproptosis, a recently identified copper-dependent form of regulated cell death, is closely associated with mitochondrial metabolic dysfunction and offers new opportunities for synergistic cancer therapy. Herein, we report a multifunctional nanoplatform (ICCP NPs) that integrates SDT, cuproptosis induction, and near-infrared (NIR) fluorescence imaging for precise and visualized cancer theranostics. The nanoplatform utilizes CuS nanocarriers to co-encapsulate the sonosensitizer chlorin e6 (Ce6) and the near-infrared fluorescent dye IR808, with surface modification by DSPE-PEG
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