Evidence map›Paper›PMID 41800411›Full record

ArticleFrontiers in microbiology2026

Exploring specific biomarkers in blood for

Carlos Velasco, Alvaro Roy, Fatima Cruz-Lopez, Alberto Gomez-Buendia, Javier Ortega, Sofía Mendez-Lopez, Lucia de Juan, Lucas Dominguez, Beatriz Romero, Julio Alvarez and 1 more

Abstract read
In one paragraph

Article in Frontiers in microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Carlos VelascoVISAVET Health Surveillance Centre, Complutense University of Madrid, Madrid, Spain.
Alvaro RoyCentro Nacional de Epidemiología, Instituto de Salud Carlos III, Madrid, Spain.
Fatima Cruz-LopezVISAVET Health Surveillance Centre, Complutense University of Madrid, Madrid, Spain.
Alberto Gomez-BuendiaVISAVET Health Surveillance Centre, Complutense University of Madrid, Madrid, Spain.
Javier OrtegaVISAVET Health Surveillance Centre, Complutense University of Madrid, Madrid, Spain.
Sofía Mendez-LopezVISAVET Health Surveillance Centre, Complutense University of Madrid, Madrid, Spain.
Lucia de JuanVISAVET Health Surveillance Centre, Complutense University of Madrid, Madrid, Spain.
Lucas DominguezVISAVET Health Surveillance Centre, Complutense University of Madrid, Madrid, Spain.
Beatriz RomeroVISAVET Health Surveillance Centre, Complutense University of Madrid, Madrid, Spain.
Julio AlvarezVISAVET Health Surveillance Centre, Complutense University of Madrid, Madrid, Spain.
Javier BezosVISAVET Health Surveillance Centre, Complutense University of Madrid, Madrid, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Caprine tuberculosis (cTB) is a zoonotic disease with significant implications for animal and public health and economic impact. Therefore, accurate ante-mortem diagnosis is essential. Diagnosis in goats rely on the single and comparative intradermal tuberculin test (SITT and CITT, respectively), both of which showing limited diagnostic performance. The aim of the study was to characterize the immune and physiological responses to cTB in naturally infected goats and to identify potential Methodology: The study was conducted in a cTB infected herd and goats were classified as reactors (positive to SITT or IFN-γ release assay and considered as infected) and non-reactors. Basal production of fifteen key immune cytokines was measured in plasma samples ( Results and discussion: Regarding cytokine expression patterns, plasma levels of IFN-γ and IFN-γ-inducible protein 10 (IP-10) in PPDb-stimulated samples were significantly higher (

Indexed as

acute phase proteinscomplete blood countdiagnosisgoatIFN-γIP-10oxidative stresstuberculosis

Identifiers

PMID41800411
PMCPMC12963342

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.