ArticleFrontiers in microbiology2026
Ferroptosis-mediated intestinal decolonization of
Article in Frontiers in microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Klebsiella pneumoniae (KP) is a Gram-negative bacterium with a thick capsule that confers natural drug resistance, making it a common opportunistic pathogen. In recent years, the spread of Methods: This study introduces an iron-polypyrrole nanocomposite (Fe/PPy) designed to leverage an innovative mechanism of ferroptosis-induced bacterial killing. The nanomaterial possesses intrinsic Fenton reaction activity. Moreover, its photothermal conversion efficiency exceeds 85%. Under 1,064 nm near-infrared (NIR) light, its photothermal effect significantly enhances the Fenton reaction efficiency, thereby effectively catalyzing the conversion of bacterial endogenous H₂O₂ into reactive oxygen species (ROS), thereby inducing bacterial lipid peroxidation and achieving targeted bacterial killing via the ferroptosis pathway. Results: The excellent tissue penetration of 1,064 nm NIR light enables this material to act precisely on deep-seated infectious lesions, achieving Discussion: This study provides a novel nanodrug design approach for the clinical treatment of KP infections, offering significant translational potential in the field of anti-infective therapy.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.