Evidence map›Paper›PMID 41800360›Full record

ArticleCrystal growth & design2026

Multicomponent Oxicam-Metformin Salts: Toward a Strategy for Enhancing Solubility and Stability.

Estephany Muñoz-Hernández, Carolina Alarcón-Payer, Antonio Frontera, Antonio Rodríguez-Diéguez, Francisco J Acebedo-Martínez, Alicia Domínguez-Martín, Duane Choquesillo-Lazarte

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Crystal growth & design, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Estephany Muñoz-HernándezLaboratorio de Estudios Cristalográficos, IACT-CSIC, Avda. de las Palmeras 4, 18100 Armilla, Spain.
Carolina Alarcón-PayerServicio de Farmacia, Hospital Universitario Virgen de las Nieves, 18014 Granada, Spain.
Antonio FronteraDepartament de Química, Universitat de les Illes Balears, Crta. de Valldemossa km 7.5, 07122 Palma, Spain.ORCID https://orcid.org/0000-0001-7840-2139
Antonio Rodríguez-DiéguezDepartment of Inorganic Chemistry, Faculty of Sciences, University of Granada, 18071 Granada, Spain.ORCID https://orcid.org/0000-0003-3198-5378
Francisco J Acebedo-MartínezLaboratorio de Estudios Cristalográficos, IACT-CSIC, Avda. de las Palmeras 4, 18100 Armilla, Spain.
Alicia Domínguez-MartínDepartment of Inorganic Chemistry, Faculty of Pharmacy, University of Granada, 18071 Granada, Spain.ORCID https://orcid.org/0000-0001-8669-6712
Duane Choquesillo-LazarteLaboratorio de Estudios Cristalográficos, IACT-CSIC, Avda. de las Palmeras 4, 18100 Armilla, Spain.ORCID https://orcid.org/0000-0002-7077-8972

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Drug-drug pharmaceutical multicomponent materials (PMMs) offer a promising strategy to modulate the physicochemical properties of active pharmaceutical ingredients, while enabling synergistic effects and combination therapy. Here, we report the preparation and full characterization of a new family of oxicam-metformin (

Identifiers

PMID41800360
PMCPMC12965098

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.