ArticleFrontiers in surgery2026
Accuracy and safety of navigated pedicle screw insertion in cervical spine fractures.
Article in Frontiers in surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Who cites it
1 citing paper in PubMed.
- Machine-Learning-Based Prediction of Cervical Pedicle Screw Malposition from Clinical and Anatomical Features.Journal of clinical medicine · 2026Article
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Pedicle screw (PS) fixation provides superior biomechanical stability compared with lateral mass screw (LMS) fixation for unstable cervical spine fractures (CS-Fx) but is associated with a risk of neurovascular injury. Navigation systems have improved PS placement accuracy, although most published studies remain small and underpowered to assess rare complications. Objective: To evaluate the accuracy and safety of navigation-assisted PS fixation for unstable CS-Fx in a population-based cohort. Methods: All consecutive patients with unstable CS-Fx who underwent navigated PS fixation at Oslo University Hospital between 2015 and 2024 were included in this study. Navigation was performed using preoperative CT-based surface matching. Postoperative CT scans obtained within 24 h were used to grade PS accuracy as Grade 1 (<2 mm breach), Grade 2 (2-4 mm), or Grade 3 (>4 mm). Complications related to PS placement were recorded. Results: A total of 345 patients (median age 68 years; 75% males) underwent fixation with 1,347 navigated PSs. Screw accuracy was Grade 1 in 90% of cases, Grade 2 in 8% of cases, and Grade 3 in 2% of cases. Surgery-related complications occurred in 23 patients (6.7%), of whom 11 experienced complications directly related to PS placement. The per-screw complication risk was 0.8%, increasing with decreasing accuracy: 0.1% (Grade 1), 6% (Grade 2), and 14% (Grade 3). Vertebral artery injury occurred in seven patients; two patients experienced new-onset nerve root injury, one had a misplaced screw breaching the atlanto-occipital joint, and one developed significant perioperative bleeding. No cases of new-onset spinal cord injury or screw pull-out were observed. Surgical site infections occurred in 3.5% of patients and were successfully treated with debridement and antibiotics in all cases, without the need for implant removal. Conclusion: Navigated cervical PS fixation is accurate and associated with a low rate of serious complications. Meticulous planning and surgical technique remain essential despite the use of navigation assistance.
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