Evidence map›Paper›PMID 41800332›Full record

ArticleProceedings of SPIE--the International Society for Optical Engineering2025

A simplified fluorescence assay to estimate binding on- and off-rates for molecular targeted imaging agents.

A S Chalmika Sarathchandra, Ranuli C Abeysinghe, Sassan Hodge, Kimberley S Samkoe, Geoffrey P Luke, Kenneth M Tichauer

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Proceedings of SPIE--the International Society for Optical Engineering, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

A S Chalmika SarathchandraDepartment of Biomedical Engineering, Illinois Institute of Technology, Chicago IL, USA 60616.
Ranuli C AbeysingheThayer School of Engineering, Dartmouth College, Hanover, NH,USA 03755.
Sassan HodgeThayer School of Engineering, Dartmouth College, Hanover, NH,USA 03755.
Kimberley S SamkoeThayer School of Engineering, Dartmouth College, Hanover, NH,USA 03755.
Geoffrey P LukeThayer School of Engineering, Dartmouth College, Hanover, NH,USA 03755.
Kenneth M TichauerDepartment of Biomedical Engineering, Illinois Institute of Technology, Chicago IL, USA 60616.

Funding

Multiplex Ultrasound Imaging for the Detection of Head and Neck Lymph Node MicrometastasesR01DE033175 · NIDCR · DARTMOUTH COLLEGE · PI Geoffrey P. Luke · 2024 to 2026
$1.7M
NIDCR NIH HHS R01 DE033175
6 · The paper itself

Abstract

Accurate

Indexed as

Binding affinity assayBinding on- and off-rates (kon and koff)Epidermal growth factor receptor (EGFR)Fluorescent molecular imaging agentHead and neck cancer

Identifiers

PMID41800332
PMCPMC12965209

What OpenQuestion holds

Textmetadata
LicenceTDM
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.