Evidence map›Paper›PMID 41800277›Full record

ArticleCase reports in oncological medicine2026

Primary Mediastinal Seminoma: A Diagnostic and Therapeutic Challenge With an Optimistic Outcome.

Stephanie Dos Santos Bueno, Roberta Borin Previtale, Mike Rocha Alves, Klinger Soares Faico-Filho

Abstract read
In one paragraph

Article in Case reports in oncological medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Stephanie Dos Santos BuenoDepartment of Internal Medicine and Laboratory Medicine, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, Brazil, unifesp.br.ORCID https://orcid.org/0009-0004-5337-1267
Roberta Borin PrevitaleDepartment of Internal Medicine and Laboratory Medicine, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, Brazil, unifesp.br.ORCID https://orcid.org/0009-0009-1131-1182
Mike Rocha AlvesDepartment of Internal Medicine and Laboratory Medicine, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, Brazil, unifesp.br.ORCID https://orcid.org/0009-0009-9822-1154
Klinger Soares Faico-FilhoDepartment of Internal Medicine and Laboratory Medicine, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, Brazil, unifesp.br.ORCID https://orcid.org/0000-0003-2071-0061

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Primary mediastinal seminoma is a rare germ cell tumor that predominantly affects young men. Clinical presentation is variable, and diagnosis relies on imaging studies, tumor markers, and histopathological confirmation. This case report describes the diagnostic and therapeutic approach in a patient with mediastinal seminoma, in accordance with CARE guidelines. Case Report: A 33-year-old man presented with hoarseness, progressive dyspnea, dysphagia, and cough. Diagnostic investigation revealed a large mass in the anterior and middle mediastinum, which was confirmed as seminoma by biopsy and immunohistochemical analysis. Treatment with cisplatin-based chemotherapy (BEP regimen) resulted in a favorable response and significant tumor reduction. Conclusion: Early diagnosis and appropriate treatment of primary mediastinal seminoma are essential for achieving a favorable prognosis.

Indexed as

CARE guidelinescase reportgerm cell neoplasmsmediastinumseminoma

Identifiers

PMID41800277
PMCPMC12966336

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.