ArticleMayo Clinic proceedings. Innovations, quality & outcomes2026
Microwave Ablation Versus Thyroid Lobectomy for Solitary cT1aN0M0 Papillary Thyroid Carcinoma: A Prospective Multicenter Cohort Study.
Article in Mayo Clinic proceedings. Innovations, quality & outcomes, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04197960 (A Prospective Multicenter Study to Compare the Therapeutic Outcomes of Microwave Ablation With Surgical Resection for Micropapillary Thyroid Carcinoma), which is not on this map. Cited by 1 paper, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Prospective Multicenter Study to Compare the Therapeutic Outcomes of Microwave Ablation With Surgical Resection for Micropapillary Thyroid Carcinoma
Who cites it
1 citing paper in PubMed, 1 synthesis or guideline pooled it.
- Image-Guided Thyroid Ablation versus Surgery for T1N0M0 Papillary Thyroid Carcinoma: A Consensus-Aligned Systematic Review and Meta-Analysis.Balkan medical journal · 2026Pooled it
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: To determine whether thermal ablation could serve as an alternative to surgery in solitary clinically node-uninvolved papillary thyroid carcinoma ≤1 cm (cT1aN0M0 PTC). Patients and Methods: This comparative study was performed across 12 tertiary hospitals and enrolled patients from December 1, 2019 to December 31, 2020. A total of 895 patients with cT1aN0M0 PTC were enrolled and assigned to either the microwave ablation (MWA) group or the surgery group after multidisciplinary consultation. Primary outcomes, including the disease progression, tumor volume changes, complications, and postoperative quality of life, were compared. Subgroup analyses and multimode analysis were performed. Results: Total of 444 patients in the MWA group and 439 in the surgery group were included in the final analysis. The disease progression rate was 1.14% in the surgery group and 2.48% in the MWA group with a mean follow-up of 42 months. The noninferiority of MWA to surgery was not statistically significant ( Conclusion: The MWA achieved noninferior clinical efficacy compared with thyroid lobectomy for cT1aN0M0 PTC, with faster recovery, lower cost, and fewer anxiety-related concerns. The MWA may serve as a de-escalation treatment option for patients seeking nonsurgical treatment. Trial Registration: Clinicaltrials.gov Identifier: NCT04197960.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.