Evidence map›Paper›PMID 41800197›Full record

ArticleFrontiers in sports and active living2026

The effect of aerobic exercise with blood flow restriction on substrate utilization and energy expenditure.

Jakob D Lauver, Nathen Andrews, Chase Harris, Nelo E Zanchi, Kelly E Johnson, Timothy R Rotarius, Justin P Guilkey

Abstract read
In one paragraph

Article in Frontiers in sports and active living, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jakob D LauverCollege of Health, Ball State University, Muncie, IN, United States.
Nathen AndrewsDepartment of Kinesiology, Coastal Carolina University, Conway, SC, United States.
Chase HarrisDepartment of Kinesiology, Coastal Carolina University, Conway, SC, United States.
Nelo E ZanchiDepartment of Physical Education, Federal University of Maranhao (UFMA), Sao Luis, Brazil.
Kelly E JohnsonDepartment of Kinesiology, Coastal Carolina University, Conway, SC, United States.
Timothy R RotariusDepartment of Kinesiology, Coastal Carolina University, Conway, SC, United States.
Justin P GuilkeyDepartment of Kinesiology, Coastal Carolina University, Conway, SC, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: This study examined the effects of intermittent blood flow restriction (LI-BFR) compared to low- (LI) and high-intensity interval exercise (HI) on substrate utilization and energy expenditure (EE). Methods: Exercise protocols consisted of 2-minute work intervals interspersed with 1-minute recovery intervals (20W), HI consisted of 5 intervals performed at a workload corresponding to 140% of ventilatory threshold intensity and LI and LI-BFR consisted of 10 intervals performed at 70% of ventilatory threshold. BFR cuffs were inflated to 80% of limb occlusion pressure during each work interval and deflated during each recovery. Following each exercise protocol subjects rested for three hours, during which excess EE and substrate utilization were measured. For all comparisons, statistical significance was set at Results: Fat oxidation rate was significantly greater in LI-BFR (0.11 ± 0.03 g min Conclusion: This study suggests that the addition of BFR to low-intensity results in increased fat oxidation following exercise as well as increased EE. The observed increased fat oxidation and EE could potentially have significant long-term effects on weight management.

Indexed as

carbohydrate oxidationcyclingexcess energy expenditureexcess post-exercise oxygen consumptionfat oxidation

Identifiers

PMID41800197
PMCPMC12962658

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.