ReviewFrontiers in bioengineering and biotechnology2026
Frontiers in fungal phosphatases: molecular diversity, regulatory mechanisms, analytical methodologies, ecological significance, and prospects for sustainable utilization.
Review in Frontiers in bioengineering and biotechnology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Protein Tyrosine Phosphatase Regulates Sporulation, Trap Morphogenesis, Stress Responses, and Secondary Metabolism inJournal of fungi (Basel, Switzerland) · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Phosphorus is an indispensable macronutrient essential for all forms of life, as it plays a central role in cellular energy metabolism, nucleic acid synthesis, and structural integrity. Since organisms can only absorb dissolved inorganic phosphate, the phosphatase enzyme is important in the process of converting organic phosphorus into forms that are bioavailable. Fungal phosphatases are a vastly diverse and heterogeneous functional and structural category that catalyzes the liberation of phosphates in a wide variety of organic compounds and facilitates the mobilization of phosphorus in the soil and symbiotic interactions. This review summarizes the existing information on fungal phosphatases, their classification, molecular regulation, methods of their analysis, ecological significance, and biotechnological use. Bibliometric analysis has been conducted using 3,944 publications published between 1944 and June-2025, and the analysis rate has shown an increase of 7.11% which indicates the rising relevance of the research. Phosphate-sensitive transcriptional networks (PHO/PHR pathways), nutrient signaling (TOR), MAPK cascades, and post-translational modifications control their activity. Analytical methods have either the traditional colorimetric assays or fluorometric and omics-based ones, such as transcriptomics and proteomics. These enzymes mediate organic phosphorus mineralization, symbiotic nutrient exchange in mycorrhizal systems, saprotrophic decomposition, and global phosphorus cycling, which are ecologically relevant. Its uses would be in biofertilizers, soil nutrient management, recovery of phosphorus in waste, industrial bioprocesses, and climate-smart agriculture. Nevertheless, a number of gaps exist in terms of the phosphatase diversity in non-model fungi, complexity of regulatory networks, and methodological sophistication. To promote sustainable phosphorus management, the combination of molecular, ecological and applied viewpoints is a requirement, especially due to the global exhaustion of phosphorus resources and the necessity of environmental sustainability.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.