Evidence map›Paper›PMID 41800091›Full record

ArticleFrontiers in pharmacology2026

Thalamic distribution and effects of 5-HT2C receptors on tonic GABAA inhibition and absence seizures: implications for treatment.

Anna Cavaccini, Marcello Venzi, Cristiano Bombardi, Vincenzo Crunelli, Giuseppe Di Giovanni

Abstract read
In one paragraph

Article in Frontiers in pharmacology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Anna CavacciniNeuroscience Division, School of Bioscience, Cardiff University, Cardiff, United Kingdom.
Marcello VenziNeuroscience Division, School of Bioscience, Cardiff University, Cardiff, United Kingdom.
Cristiano BombardiDepartment of Veterinary Medical Science, University of Bologna, Bologna, Italy.
Vincenzo CrunelliNeuroscience Division, School of Bioscience, Cardiff University, Cardiff, United Kingdom.
Giuseppe Di GiovanniNeuroscience Division, School of Bioscience, Cardiff University, Cardiff, United Kingdom.

Funding

Wellcome Trust
6 · The paper itself

Abstract

Introduction: Childhood absence epilepsy (CAE) is associated with abnormal thalamocortical oscillations and enhanced GABAergic function in the ventrobasal (VB) thalamus, including increased extrasynaptic GABA Methods: 5-HT Results: No differences in 5-HT Discussion: These findings indicate that 5-HT

Indexed as

GAERS ratsnucleus reticularis thalamiRo 60-0175SB242084spike-and-wave dischargesthalamocortical neuronsventrobasal complex

Identifiers

PMID41800091
PMCPMC12963287

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.