ArticleInternational journal of clinical pediatric dentistry2026
Efficacy and Pain Perception of a Comfort-in™ for Palatal Anesthesia in Pediatric Dental Patients: A Randomized Controlled Trial.
Article in International journal of clinical pediatric dentistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07585812 (Assessing the Efficacy of the Comfort-in Needle-Free Injection System for Managing Pain and Anxiety During Pediatric Dental Injections), which is not on this map. Not yet cited in PubMed.
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Assessing the Efficacy of the Comfort-in Needle-Free Injection System for Managing Pain and Anxiety During Pediatric Dental Injections: A Randomized Split-Mouth Clinical Trial
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6 authors.
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Abstract
Background: Needle phobia is frequently observed in children, contributing to heightened dental anxiety, uncooperative behavior, and care avoidance. The sight or sensation of traditional anesthesia needles can provoke intense emotional responses, complicating pediatric pain management. This study assesses the Comfort-in™ needle-free jet injector as an alternative, aiming to enhance anesthetic delivery, patient comfort, and cooperation during pediatric dental procedures. Aim: To assess the effectiveness of the Comfort-in™ system in minimizing pain during local anesthesia (LA) administration in pediatric dental procedures. Materials and methods: This randomized controlled trial included 64 children aged 4-9 years undergoing tooth extractions involving buccal and palatal infiltrations. Participants were randomly assigned to receive anesthesia Results: The difference in pulse rates during LA administration and during treatment was statistically significant between the two groups ( Conclusion: Considering the limitations of the present study, the Comfort-in™ system demonstrated effectiveness as a needle-free alternative for minimizing pain and anxiety in pediatric patients, while also significantly reducing the time required for LA administration. How to cite this article: Naik SS, Kodical SR, Joshi A,
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