Evidence map›Paper›PMID 41799975›Full record

ReviewFrontiers in plant science2026

Cytochrome P450 gene family: cross-pathway functional conservation, novel catalytic reactions, and synthetic biology-driven applications in plant secondary metabolism.

Lang Chen, Yingying Zhao, Sujing He, Jialing Lei, Hongwei Li, Zhizhai Liu, Liang Zhang, Liwen Yang, Kuanping Deng, Runlan Wan and 1 more

Abstract readReview
In one paragraph

Review in Frontiers in plant science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Lang ChenDepartment of Medical Instrumental Analysis, School of Preclinical Medicine of Zunyi Medical University, Zunyi, Guizhou, China.
Yingying ZhaoZunyi Academy of Agricultural Sciences, Zunyi, Guizhou, China.
Sujing HeDepartment of Medical Instrumental Analysis, School of Preclinical Medicine of Zunyi Medical University, Zunyi, Guizhou, China.
Jialing LeiDepartment of Medical Instrumental Analysis, School of Preclinical Medicine of Zunyi Medical University, Zunyi, Guizhou, China.
Hongwei LiDepartment of Medical Instrumental Analysis, School of Preclinical Medicine of Zunyi Medical University, Zunyi, Guizhou, China.
Zhizhai LiuCollege of Agronomy and Biotechnology of Southwest University, Chongqing, China.
Liang ZhangSchool of Food and Bioengineering, Food Microbiology Key Laboratory of Sichuan Province, Xihua University, Chengdu, China.
Liwen YangSchool of Medicine, Southwest Jiaotong University, Chengdu, China.
Kuanping DengZunyi Academy of Agricultural Sciences, Zunyi, Guizhou, China.
Runlan WanThe Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, China.
Delin XuDepartment of Medical Instrumental Analysis, School of Preclinical Medicine of Zunyi Medical University, Zunyi, Guizhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Plant secondary metabolites play fundamental roles in plant defense and environmental adaptation, and possess extensive high-value applications in medicine, agriculture, and industrial biotechnology. The cytochrome P450 (CYPs) family occupies a central position in metabolic networks by catalyzing key reactions in the biosynthesis of terpenoids, alkaloids, and flavonoids. Although the role of CYPs in these pathways is well documented, their precise catalytic mechanisms and regulatory networks remain poorly characterized. In this review, we summarize recent advances in CYP classification, structural features, and catalytic diversity across plant species. We also analyze the transcriptional regulation and environmental signals that control

Indexed as

biosynthesisCYPscytochrome P450 enzymesengineering applicationgene regulationsecondary metabolites

Identifiers

PMID41799975
PMCPMC12963337

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.