Evidence map›Paper›PMID 41799960›Full record

ArticleBioactive materials2026

Degradation-tunable coating with sustained silver release for spinal implants to prevent postoperative infections.

Kecheng Quan, Ting Zhang, Xingyu Zhou, Shanshan Liu, Zhinan Mao, Jiang Sun, Shilin Xue, Xingchen Yao, Yinglun Tian, Cheng Zhang and 6 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Bioactive materials, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Kecheng QuanDepartment of Orthopaedics, Peking University Third Hospital, Beijing, 100191, PR China.
Ting ZhangSchool of Materials Science and Engineering, Peking University, Beijing, 100871, PR China.
Xingyu ZhouPeking University Health Science Center, Beijing, 100191, PR China.
Shanshan LiuDepartment of Orthopaedics, Peking University Third Hospital, Beijing, 100191, PR China.
Zhinan MaoSchool of Materials Science and Engineering, Peking University, Beijing, 100871, PR China.
Jiang SunDepartment of Orthopaedics, Peking University Third Hospital, Beijing, 100191, PR China.
Shilin XueDepartment of Orthopaedics, Peking University Third Hospital, Beijing, 100191, PR China.
Xingchen YaoDepartment of Orthopaedics, Peking University Third Hospital, Beijing, 100191, PR China.
Yinglun TianDepartment of Orthopaedics, Peking University Third Hospital, Beijing, 100191, PR China.
Cheng ZhangDepartment of Orthopaedics, Peking University Third Hospital, Beijing, 100191, PR China.
Jian HeDepartment of Orthopaedics, Peking University Third Hospital, Beijing, 100191, PR China.
Dingbang XieDepartment of Orthopaedics, Peking University Third Hospital, Beijing, 100191, PR China.
Weishi LiDepartment of Orthopaedics, Peking University Third Hospital, Beijing, 100191, PR China.
Shenglin WangDepartment of Orthopaedics, Peking University Third Hospital, Beijing, 100191, PR China.
Yufeng ZhengSchool of Materials Science and Engineering, Peking University, Beijing, 100871, PR China.
Nanfang XuDepartment of Orthopaedics, Peking University Third Hospital, Beijing, 100191, PR China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Irreducible atlantoaxial dislocation is a challenging condition for spine surgeons and carries a particularly high risk of postoperative infection due to its trans-oral approach for peri-odontoid soft tissue release. Conventional antibacterial implant coatings are limited by rapid burst release, leading to short-term efficacy and potential cytotoxicity. To address this, we developed a composite coating of silver nanoparticle-decorated ZIF-8 (AgZ) within a tunable methacrylate gelatin (GelMA) and silk fibroin (SF) matrix (AgZ/GelSF) for 3D-printed Ti-6Al-4V fusion cages. The AgZ nanocomposite enhanced silver dispersibility and potency, reducing the minimum bactericidal concentration against MRSA and

Indexed as

Antibacterial coatingAtlantoaxial dislocationControlled drug releaseImplant-associated infectionsSilver nanoparticles

Identifiers

PMID41799960
PMCPMC12964024

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.