Evidence map›Paper›PMID 41799957›Full record

ArticleBioactive materials2026

Glycosylated graphene-nylon fiber: A new material platform to balance the nanotoxicity and bioactivity for anti-infective therapy.

Gefei Li, Juan Mo, Jie Jing, Lucen Li, Yuhao Ju, Wenxiao Ma, Ziyao Zhuang, Xuanxuan Yu, Jie Deng, Jing Lin and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Bioactive materials, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Gefei LiCollege of Science, Nanjing Forestry University, Nanjing, 210037, China.
Juan MoState Key Laboratory of Natural and Biomimetic Drugs, Beijing Key Laboratory of Carbohydrate Intelligent Manufacture and Functional Applications, School of Pharmaceutical Sciences, Peking University, Beijing, 100191, China.
Jie JingCollege of Science, Nanjing Forestry University, Nanjing, 210037, China.
Lucen LiCollege of Science, Nanjing Forestry University, Nanjing, 210037, China.
Yuhao JuState Key Laboratory of Natural and Biomimetic Drugs, Beijing Key Laboratory of Carbohydrate Intelligent Manufacture and Functional Applications, School of Pharmaceutical Sciences, Peking University, Beijing, 100191, China.
Wenxiao MaState Key Laboratory of Natural and Biomimetic Drugs, Beijing Key Laboratory of Carbohydrate Intelligent Manufacture and Functional Applications, School of Pharmaceutical Sciences, Peking University, Beijing, 100191, China.
Ziyao ZhuangNanjing Stomatological Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, 210009, China.
Xuanxuan YuNanjing Stomatological Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, 210009, China.
Jie DengNanjing Stomatological Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, 210009, China.
Jing LinNanjing Institute of Metrological Supervision and Testing, Nanjing, 210049, China.
Wei LiCollege of Environment and Ecology, Chongqing University, Chongqing, 400045, China.
Zhenyang LuoCollege of Science, Nanjing Forestry University, Nanjing, 210037, China.
Yan JiangHighbery New Nano Materials Technology Co., Ltd., Changzhou, 213000, China.
Shin-Ichiro ShodaDepartment of Biomolecular Engineering, Graduate School of Engineering, Tohoku University, Sendai, 980-8579, Japan.
Xin-Shan YeState Key Laboratory of Natural and Biomimetic Drugs, Beijing Key Laboratory of Carbohydrate Intelligent Manufacture and Functional Applications, School of Pharmaceutical Sciences, Peking University, Beijing, 100191, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nanomaterials show great potential for biomedical applications, particularly in addressing challenges such as drug-resistant bacterial infections. However, their clinical use is hindered by considerable obstacles, mainly due to the potential risks associated with nanotoxicity. One effective strategy to mitigate nanotoxicity is the use of nanocomposites, which involve dispersing and immobilizing nanomaterials within polymer matrices. Unfortunately, it often results in a significant reduction in bioactivity. To overcome the challenge of balancing nanotoxicity and bioactivity, novel glycosylated graphene-nylon fibers were designed and synthesized by using an in situ polymerization technique combined with the surface glycan-engineering. By covalently immobilizing graphene nanosheets within the polyamide matrix, the potential health risks associated with graphene migration

Indexed as

Anti-infective therapyGrapheneIn situ polymerizationInterfacial glycosylationNylon fiber

Identifiers

PMID41799957
PMCPMC12964391

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.