Evidence map›Paper›PMID 41799955›Full record

ArticleBioactive materials2026

Bone matrix-inspired whitlockite porous ceramic with effects of autophagy activation contributes to bone regeneration.

Yuyi Wang, Cong Feng, Zemin Hou, Puxin Liu, Chuyao Xu, Xuening Chen, Zhengyong Li, Yumei Xiao, Xiangfeng Li, Xiangdong Zhu and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Bioactive materials, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Yuyi WangNational Engineering Research Center for Biomaterials, College of Biomedical Engineering Sichuan University, 29# Wangjiang Road, 610064, China.
Cong FengNational Engineering Research Center for Biomaterials, College of Biomedical Engineering Sichuan University, 29# Wangjiang Road, 610064, China.
Zemin HouDepartment of Burn and Plastic Surgery, West China Hospital, Sichuan University, Chengdu, 610041, China.
Puxin LiuNational Engineering Research Center for Biomaterials, College of Biomedical Engineering Sichuan University, 29# Wangjiang Road, 610064, China.
Chuyao XuNational Engineering Research Center for Biomaterials, College of Biomedical Engineering Sichuan University, 29# Wangjiang Road, 610064, China.
Xuening ChenNational Engineering Research Center for Biomaterials, College of Biomedical Engineering Sichuan University, 29# Wangjiang Road, 610064, China.
Zhengyong LiDepartment of Burn and Plastic Surgery, West China Hospital, Sichuan University, Chengdu, 610041, China.
Yumei XiaoNational Engineering Research Center for Biomaterials, College of Biomedical Engineering Sichuan University, 29# Wangjiang Road, 610064, China.
Xiangfeng LiNational Engineering Research Center for Biomaterials, College of Biomedical Engineering Sichuan University, 29# Wangjiang Road, 610064, China.
Xiangdong ZhuNational Engineering Research Center for Biomaterials, College of Biomedical Engineering Sichuan University, 29# Wangjiang Road, 610064, China.
Kai ZhangNational Engineering Research Center for Biomaterials, College of Biomedical Engineering Sichuan University, 29# Wangjiang Road, 610064, China.
Antonios G MikosDepartment of Bioengineering, Rice University, Houston, 77251, TX, USA.
Xingdong ZhangNational Engineering Research Center for Biomaterials, College of Biomedical Engineering Sichuan University, 29# Wangjiang Road, 610064, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Whitlockite (WH), a natural magnesium-containing calcium phosphate second in abundance only to hydroxyapatite (HAp) in the inorganic phase of bone tissue, has attracted great attention in bone repair recently. Previous studies have shown that porous structures play a pivotal role in bone defect repair using biomaterials. However, the traditional fabrication process of porous ceramic through high-temperature sintering frequently results in the dehydration and breakdown of WH. To overcome this challenge, we develop an innovative fabrication of porous whitlockite ceramic

Indexed as

AngiogenesisAutophagyBone regenerationMechanismOsteogenesisPhase transformationWhitlockite porous ceramic

Identifiers

PMID41799955
PMCPMC12963904

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.