Evidence map›Paper›PMID 41799936›Full record

ArticleMedComm2026

Trans-Omics Integration Reveals That the Kidney Contributes to Systemic Aging via Sexually Dimorphic Accumulation of Glycosphingolipids.

Zhen Ni, Chenyin Cao, Yanlin Tian, Jinming Mu, He Tian, Zehua Wang, Shaohua Zhang, Mingjun Cao, Yuntian Yang, Wei Ling Florence Lim and 9 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in MedComm, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Zhen NiState Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences Beijing China.ORCID https://orcid.org/0000-0003-0248-4523
Chenyin CaoState Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences Beijing China.
Yanlin TianState Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences Beijing China.
Jinming MuState Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences Beijing China.
He TianGuangzhou National Laboratory Guangzhou China.
Zehua WangGuangzhou National Laboratory Guangzhou China.
Shaohua ZhangState Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences Beijing China.
Mingjun CaoState Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences Beijing China.
Yuntian YangGuangzhou National Laboratory Guangzhou China.
Wei Ling Florence LimJiangsu Provincial Key Laboratory of Molecular Targets and Intervention for Metabolic Diseases LipidALL Technologies Company Limited Changzhou China.ORCID https://orcid.org/0000-0002-8988-2147
Jingkang CuiJiangsu Provincial Key Laboratory of Molecular Targets and Intervention for Metabolic Diseases LipidALL Technologies Company Limited Changzhou China.ORCID https://orcid.org/0009-0004-7963-7721
Huan SunState Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences Beijing China.
Huan MiaoState Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences Beijing China.
Yuan WangBeijing Anzhen Hospital Capital Medical University Beijing China.
Jie DuBeijing Anzhen Hospital Capital Medical University Beijing China.
Timothy KwokDepartment of Medicine and Therapeutics The Chinese University of Hong Kong, Prince of Wales Hospital Shatin China.
Huan ChenBeijing Life Science Academy Beijing China.
Sin Man LamJiangsu Provincial Key Laboratory of Molecular Targets and Intervention for Metabolic Diseases LipidALL Technologies Company Limited Changzhou China.
Guanghou ShuiState Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences Beijing China.ORCID https://orcid.org/0000-0002-1621-9643

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Age-associated deterioration of physiological functions occurs at heterogeneous rates across individual organs. A granular evaluation of systemic metabolic mediators of aging in a healthy human cohort (

Identifiers

PMID41799936
PMCPMC12966803

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.