Evidence map›Paper›PMID 41799836›Full record

ArticleESMO real world data and digital oncology2026

Comparing artificial intelligence and multidisciplinary tumor board decision making in real-world cancer care: a prospective blinded concordance study.

R Pinninti, R Gullapalli, K M Mallavarapu, R Singareddy, S S Nekkanti, P Nikhil, S Shukla, N Hariharan, D Gudipudi, K Suseela and 3 more

Abstract read
In one paragraph

Article in ESMO real world data and digital oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

R PinnintiDepartment of Medical Oncology, Basavatarakam Indo-American Cancer Hospital & Research Institute, Hyderabad, India.
R GullapalliDepartment of Medical Oncology, Basavatarakam Indo-American Cancer Hospital & Research Institute, Hyderabad, India.
K M MallavarapuDepartment of Medical Oncology, Basavatarakam Indo-American Cancer Hospital & Research Institute, Hyderabad, India.
R SingareddyDepartment of Radiation Oncology, Basavatarakam Indo-American Cancer Hospital & Research Institute, Hyderabad, India.
S S NekkantiDepartment of Surgical Oncology, Basavatarakam Indo-American Cancer Hospital & Research Institute, Hyderabad, India.
P NikhilDepartment of Medical Oncology, Basavatarakam Indo-American Cancer Hospital & Research Institute, Hyderabad, India.
S ShuklaDepartment of Surgical Oncology, Basavatarakam Indo-American Cancer Hospital & Research Institute, Hyderabad, India.
N HariharanDepartment of Breast Oncosurgery, Basavatarakam Indo-American Cancer Hospital & Research Institute, Hyderabad, India.
D GudipudiDepartment of Radiation Oncology, Basavatarakam Indo-American Cancer Hospital & Research Institute, Hyderabad, India.
K SuseelaDepartment of Pathology, Basavatarakam Indo-American Cancer Hospital & Research Institute, Hyderabad, India.
V KoppulaDepartment of Radiodiagnosis, Basavatarakam Indo-American Cancer Hospital & Research Institute, Hyderabad, India.
T S RaoDepartment of Surgical Oncology, Basavatarakam Indo-American Cancer Hospital & Research Institute, Hyderabad, India.
S J RajappaDepartment of Medical Oncology, Basavatarakam Indo-American Cancer Hospital & Research Institute, Hyderabad, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Multidisciplinary tumor boards (MDTs) integrate expertise, enhance diagnostic accuracy, improve adherence to evidence-based guidelines, and facilitate individualized treatment planning. Recent advances in artificial intelligence (AI) help streamline these processes, though prospective real-world evaluations remain limited. Materials and methods: We conducted a prospective, non-interventional, blinded concordance study at a tertiary cancer center. Consecutive cases discussed at institutional MDTs between January 2025 and June 2025 were screened for eligibility. Cases with comprehensive clinical information and documented MDT decisions were included. Anonymized vignettes were input into ChatGPT® using a standardized template. A blinded expert reviewer assessed concordance using a predefined three-point scale. The primary outcome was mean concordance score (MCS) for primary clinical query. Secondary outcomes were domain-specific concordance and reviewer-perceived clinical acceptability of AI decisions. Results: A total of 106 cases (median age 53 years) were analyzed, spanning 21 tumor sites, with the most common being breast (17%), ovary (10.4%), and esophagus (8.5%). Disease stages at MDT discussion were early (20.8%), locally advanced (49.1%), Conclusions: In a prospective real-world setting, moderate-high concordance was observed for AI and MDT decisions across multiple domains. These findings support further evaluation of AI as a decision-support tool within multidisciplinary oncology care.

Indexed as

artificial intelligencedecision makingoncologytumor board

Identifiers

PMID41799836
PMCPMC12962095

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.