Evidence map›Paper›PMID 41799671›Full record

ArticleJournal of hand surgery global online2026

Enhancing Hand Vascular Assessment: The Role of Hyperspectral Imaging in Perfusion Monitoring.

Ovya Ganesan, Jeffrey Trost, Michael Drake Pike, Robert D Sampson, Stephanie Holzmer, Simon Talbot, Christian E Sampson

Abstract read
In one paragraph

Article in Journal of hand surgery global online, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ovya GanesanDepartment of Plastic Surgery, Brigham and Women's Hospital, Boston, MA.
Jeffrey TrostDepartment of Plastic Surgery, McGovern Medical School at UTHealth Houston, Houston, TX.
Michael Drake PikeHarvard Medical School, Boston, MA.
Robert D SampsonDepartment of Plastic Surgery, Brigham and Women's Hospital, Boston, MA.
Stephanie HolzmerDepartment of Plastic Surgery, Brigham and Women's Hospital, Boston, MA.
Simon TalbotDepartment of Plastic Surgery, Brigham and Women's Hospital, Boston, MA.
Christian E SampsonDepartment of Plastic Surgery, Brigham and Women's Hospital, Boston, MA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Accurate assessment and monitoring of tissue perfusion are critical in diagnosing and managing vascular diseases of the hand. Traditional methods, including clinical examination, pulse oximetry, and Doppler ultrasound, have limitations in detecting early or subtle perfusion deficits. Hyperspectral imaging (HSI) is a noninvasive, real-time technology that generates quantitative perfusion maps by measuring oxygen saturation, oxyhemoglobin, and deoxyhemoglobin levels. To the best of our knowledge, this is the first study of its kind to evaluate the clinical use of HSI in assessing perfusion abnormalities in vascular conditions of the hand and its emerging applications in hand surgery. Methods: A single center study was conducted from 2021 to 2025, involving 5 patients with various upper-extremity vascular conditions, each followed to early 2025. Perfusion images were obtained using the HyperView (HyperMed, Memphis, TN) system before and after surgical or procedural interventions. Results were compared against the contralateral hand or historical normal values from the prior-generation HyperView (OxyVu-1) system. Results: Hyperspectral imaging effectively identified perfusion deficits, guided urgent clinical decision-making, and monitored postoperative improvements. In one case, HSI demonstrated a 5% increase in tissue oxygen saturation after ulnar artery reconstruction, correlating with successful wound healing. Another patient with Raynaud's phenomenon showed a 23% perfusion increase following botulinum toxin injection. Hyperspectral imaging also detected thrombosis and monitored perioperative oxygen saturation changes in real-time. Conclusions: Hyperspectral imaging offers a novel, objective approach to perfusion assessment in hand and upper-extremity vascular disease, addressing key limitations of traditional methods. Its integration into clinical workflows holds promise for enhancing real-time, data-driven decision-making in hand surgery and vascular medicine. Type of Study/level of evidence: Diagnostic IV.

Indexed as

Hand disordersHyperspectral imagingHyperViewTissue perfusionVascular disease

Identifiers

PMID41799671
PMCPMC12966670

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.