Evidence map›Paper›PMID 41799645›Full record

ArticleReproductive medicine and biology

A Successful Live Birth After Double Fertility Preservation With Embryo Cryopreservation and MPA Therapy Combined With Hysteroscopic Resection for Metachronous Breast and Endometrial Cancer in Women With Cowden Syndrome: A Case Report.

Itsuki Kajimura, Michio Kitajima, Shoko Miura, Chiaki Eishi, Riko Matsuda, Kanako Matsumoto, Ayumi Harada, Yuriko Kitajima, Yuri Hasegawa, Megumi Matsumoto and 2 more

Abstract read
In one paragraph

Article in Reproductive medicine and biology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Itsuki KajimuraDepartment of Obstetrics and Gynecology Nagasaki University Hospital Nagasaki Japan.ORCID https://orcid.org/0000-0002-0893-3839
Michio KitajimaWoman's Medical Center, Takagi Hospital, Department of Obstetrics and Gynecology International University of Health and Welfare Okawa Japan.
Shoko MiuraDepartment of Obstetrics and Gynecology Nagasaki University Hospital Nagasaki Japan.
Chiaki EishiDepartment of Obstetrics and Gynecology Nagasaki University Hospital Nagasaki Japan.
Riko MatsudaClinical Genomics Center Department of Obstetrics and Gynecology Nagasaki University Hospital Nagasaki University Hospital Nagasaki Japan.
Kanako MatsumotoDepartment of Obstetrics and Gynecology Nagasaki University Hospital Nagasaki Japan.
Ayumi HaradaDepartment of Obstetrics and Gynecology Nagasaki University Hospital Nagasaki Japan.
Yuriko KitajimaDepartment of Obstetrics and Gynecology Nagasaki University Hospital Nagasaki Japan.
Yuri HasegawaDepartment of Obstetrics and Gynecology Nagasaki University Hospital Nagasaki Japan.
Megumi MatsumotoClinical Genomics Center Department of Obstetrics and Gynecology Nagasaki University Hospital Nagasaki University Hospital Nagasaki Japan.
Keitaro MatsumotoDivision of Surgical Oncology, Department of Surgery Nagasaki University Graduate School of Biomedical Sciences Nagasaki Japan.
Kiyonori MiuraDepartment of Obstetrics and Gynecology Nagasaki University Hospital Nagasaki Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Case: Cowden syndrome is an autosomal-dominantly inherited rare condition caused by germline pathogenic variants of the Outcome: She could receive fertility preservation for breast cancer and endometrial cancer before fertility treatment and pregnancy. Conclusion: This is the first report of live births after multiple fertility preservation therapy for metachronous breast and uterine cancer in Cowden syndrome. Appropriate genetic counseling may help the patient's decision making. The treatment plan should be discussed with diverse professionals such as oncologists, reproductive physicians, perinatologists, geneticists, and genetic counselors.

Indexed as

breast cancerCowden syndromeendometrial cancerfertility preservationhereditary tumors

Identifiers

PMID41799645
PMCPMC12963780

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.