Evidence map›Paper›PMID 41799516›Full record

ArticleOncology research2026

Pingping Hu, Zhenhao Fei, Jianhua Bai, Zhiwen Wang, Yun Jin

Abstract read
In one paragraph

Article in Oncology research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Pingping HuDepartment of Hepatopancreatobiliary Surgery, The First People's Hospital of Yunnan Province, Kunming, 650032, China.
Zhenhao FeiDepartment of Hepatopancreatobiliary Surgery, The First People's Hospital of Yunnan Province, Kunming, 650032, China.
Jianhua BaiDepartment of Hepatopancreatobiliary Surgery, The First People's Hospital of Yunnan Province, Kunming, 650032, China.
Zhiwen WangDepartment of Hepatopancreatobiliary Surgery, The First People's Hospital of Yunnan Province, Kunming, 650032, China.
Yun JinDepartment of Hepatopancreatobiliary Surgery, The First People's Hospital of Yunnan Province, Kunming, 650032, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: Pancreatic cancer (PC) is characterized by poor prognosis due to its limited treatment choices and delayed detection. Methods: Integrated bioinformatic analyses of TCGA-PAAD and GSE22780 datasets identified candidate hub genes. Prognostic relevance was assessed via Kaplan-Meier and ROC analyses. Functional experiments were performed in PANC-1 and BxPC-3 cells, including qRT-PCR, CCK-8 assay, Western blotting, Transwell assay, and apoptosis assay. Co-immunoprecipitation (Co-IP) was used to verify S100A14-S100A16 interaction. CHX chase and dual-luciferase assays were employed to assess protein stability and transcriptional activity. Results: Conclusion: This study identifies

Indexed as

Pancreatic NeoplasmsS100 ProteinsTumor Suppressor Protein p53ApoptosisCalcium-Binding ProteinsCell Line, TumorCell MovementCell ProliferationDisease ProgressionGene Expression Regulation, NeoplasticHumansPrognosisCalcium-Binding ProteinsS100A14 protein, humanS100A16 protein, humanS100 ProteinsTP53 protein, humanTumor Suppressor Protein p53p53Pancreatic cancerS100A14S100A16tumor progression

Identifiers

PMID41799516
PMCPMC12963661

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.