ArticleFrontiers in public health2026
Influence of SARS-CoV-2 reinfection on bone health in the population over 55 years old in Beijing, China: a cross-sectional study.
Article in Frontiers in public health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Despite the global prevalence of SARS-CoV-2 reinfection, relatively little is known regarding its association with osteoporosis in older adults. This study investigated the potential impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection on bone health or osteoporosis risk in adults aged 55 years and older in Beijing, China, while also exploring additional factors that may influence this association. Methods: This cross-sectional study was conducted at Beijing Ditan Hospital, Beijing, China, between August and December 2024. Patients aged ≥ 55 years with SARS-CoV-2 infections were included. Data on demographic characteristics, lifestyle habits, diet, serum contents of 25-hydroxyvitamin D (25-OH-VD), and other potential risk factors for osteoporosis were collected through structured questionnaires. Bone mineral density (BMD) was assessed using dual-energy X-ray absorptiometry (DXA). To identify the variables associated with osteoporosis, logistic regression analysis was employed. Results: Three hundred and eighty-eight patients were enrolled, comprising 272 individuals with a single SARS-CoV-2 infection and 116 with two or more infections. The results revealed that individuals who had reinfection revealed a considerably higher prevalence of osteoporosis (48.3% vs. 17.3%, Conclusion: In summary, the risk of osteoporosis among individuals with SARS-CoV-2 reinfection should be carefully monitored, and greater emphasis should be placed on early, individualized prevention and treatment strategies.
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