Evidence map›Paper›PMID 41799331›Full record

ArticleBJUI compass2026

Treatment outcomes of multidisciplinary management of recurrent urinary tract infections: A 2-year experience in a dedicated complex-UTI clinic.

Pragnitha Chitteti, Ekpeno Inyang, Ahmed Ghonaimy, Jayne Morris-Laverick, Stephanie Bezemer, Igor Kubelka, Victoria McCune, Mehwash Nadeem

Abstract read
In one paragraph

Article in BJUI compass, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Pragnitha ChittetiDepartment of Urology James Cook University Hospital Middlesbrough UK.ORCID https://orcid.org/0000-0001-6682-7092
Ekpeno InyangDepartment of Urology James Cook University Hospital Middlesbrough UK.
Ahmed GhonaimyDepartment of Urology James Cook University Hospital Middlesbrough UK.ORCID https://orcid.org/0000-0002-1873-2926
Jayne Morris-LaverickDepartment of Urology James Cook University Hospital Middlesbrough UK.
Stephanie BezemerDepartment of Urology James Cook University Hospital Middlesbrough UK.
Igor KubelkaDepartment of Microbiology James Cook University Hospital Middlesbrough UK.
Victoria McCuneDepartment of Microbiology James Cook University Hospital Middlesbrough UK.ORCID https://orcid.org/0009-0000-0807-4512
Mehwash NadeemDepartment of Urology James Cook University Hospital Middlesbrough UK.ORCID https://orcid.org/0000-0002-1427-8850

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: This work aimed to assess treatment outcomes in patients with recurrent urinary tract infections (rUTIs) managed in a dedicated multidisciplinary complex-UTI clinic. In addition, this work aimed to evaluate the impact of tailored interventions on patient-reported outcomes, including quality of life (QoL) and symptomatic improvement. Materials and Methods: A 2-year, single-centre, prospective observational cohort study was conducted in a dedicated tertiary care UTI clinic. A multidisciplinary team comprising urologists, microbiologists and specialist nurses developed individualized management plans based on thorough assessments, including patient history, physical examination and necessary investigations. Data variables included patient demographics, urine culture results with antibiotic sensitivities, investigations performed and the treatment options administered. The minimum follow-up period was 6 months after the implementation of treatment in the clinic. Pretreatment and posttreatment QoL were assessed, along with posttreatment Patient Global Impression of Improvement (PGI-I) scores. Results: A total of 211 patients (mean age: 58.3 years, 89.6% female) were included. First- and second-line treatments were effective for 71% of patients, while 29% required tertiary interventions. Post-treatment, 81% of patients reported good-to-excellent improvement on the PGI-I scale, and 70% achieved good-to-excellent QoL. Overall treatment success, defined as reduced UTI frequency or symptom resolution, was reported in 87.7% of patients. Factors such as immunosuppression and history of hospital admission for urosepsis were associated with poor treatment outcomes with statistical significance. Conclusion: Dedicated multidisciplinary UTI clinics significantly improve treatment outcomes and QoL for patients with rUTIs. The findings support broader adoption of multidisciplinary approaches, emphasizing early intervention and tailored care to optimize clinical efficiency and enhance the patient experience.

Indexed as

antimicrobial resistancededicated complex‐UTI clinicIntravesical therapymultidisciplinary approachquality of liferecurrent urinary tract infections

Identifiers

PMID41799331
PMCPMC12960744

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.