ArticleIndian journal of anaesthesia2026
Comparison of the Hypotension Prediction Index and pulse pressure variation-guided haemodynamic management for intra-operative hypotension during kidney transplant: A randomised controlled trial.
Article in Indian journal of anaesthesia, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
- Regional research impact strengthening the national academics in geographical diversities.Indian journal of anaesthesia · 2026Article
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6 authors.
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Abstract
Background and Aims: Intra-operative hypotension (IOH) adversely affects renal graft and recipient outcomes. The Hypotension Prediction Index (HPI), a machine learning-based algorithm, predicts IOH. This study compared HPI- versus pulse pressure variation (PPV)-guided haemodynamic management in kidney transplantation, hypothesising that HPI guidance would reduce intra-operative hypotension. Methods: In this single-centre randomised controlled trial, 82 patients with end-stage renal disease (ESRD) undergoing live-related kidney transplantation under general anaesthesia were randomised to HPI-guided ( Results: The results were analysed for 82 patients. The median [interquartile range (IQR)] TWA-AUT <65 mmHg was 0.10 mmHg [0.04-0.17] in the HPI group and 0.16 mmHg [0.06-0.32] in the PPV group, with a median difference of -0.05 mmHg [95% confidence interval (CI): -0.18 to 0.01; Conclusion: HPI-guided haemodynamic management did not significantly reduce the time-weighted average of intra-operative hypotension during renal transplant surgery compared to PPV-guided haemodynamic management.
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