ArticleJournal of medical biochemistry2025
Observations on the effect of enteral nutrition support on serum nutritional proteins, proinflammatory cytokines and immunoglobulins in patients with cerebral hemorrhage.
Article in Journal of medical biochemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Serum Albumin-Globulin Ratio and Rupture Status of Intracranial Aneurysms: A Case-Control Study.Journal of inflammation research · 2026Article
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: This study will analyse the changes in serum nutrient protein, a proinflammatory cytokine, and immunoglobulins before and after enteral nutrition support (ENS) in patients with intracerebral haemorrhage (ICH), which will serve as a reference for future clinics when performing ENS. Methods: This retrospective observational study included 160 patients with ICH (76 in the intermittent group and 84 in the continuous group), and changes in indicators before and after EN intervention were retrospectively analysed in both groups, including serum nutrient protein (albumin ALB, transferrin TRF, prealbumin PAB), proinflammatory cytokine (IL-1 b, IL-6, TNF-a), immunoglobulins (IgA, IgG, IgM) and gastrointestinal tolerance. Results: There was no difference in adverse reactions between the two groups during ENS (P>0.05). After ENS, ALB, TRF PAB, IgA, IgG, and IgM were significantly increased in both groups, while IL-1 b, IL-6, and TNF-a were decreased (P<0.05). After ENS, there was no difference in serum nutrient protein between the two groups (P>0.05). Still, proinflammatory cytokines were lower in the intermittent group than in the continuous group, while immunoglobulins were higher than in the intermittent group (P<0.05). Conclusions: ENS exerts neuroprotection through the "intestinal barrier repair-immune remodeling-inflammation inhibition axis".
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