ArticleACS omega2026
Triethoxysilyl-Functionalized Polyethylenimine: Its Spontaneous Cross-Linking and Drug Retention.
Article in ACS omega, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Effective antibacterial and antiviral coatings are expected to serve as effective infection control measures in medical and public environments. In this study, we investigated polyethylenimine functionalized with triethoxysilyl groups (Si-PEI) as a promising platform material to implement such coatings feasibly. Si-PEI, synthesized in ethanol in a one-pot reaction, was coated onto the material surface as a diluted solution and then spontaneously cross-linked after solvent evaporation at room temperature. The resulting water-resistant coating layer retained water-soluble antimicrobial components such as copper-(II) ions and sulfonamide antibiotics within the cross-linked network, thereby moderately suppressing their leaching due to casual water exposure. Similar retention was also implemented for the antiviral agent didecyldimethylammonium chloride, and the coating layer demonstrated effective and stable suppression of viral infectivity of deposited droplets under realistic conditions.
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Registered trials
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