Evidence map›Paper›PMID 41799060›Full record

ArticleACS omega2026

Beyond MIDAS: An

Francisco Das Chagas Pereira de Andrade, Yago Ferreira E Silva, Paulo Ricardo Batista, Anderson Nogueira Mendes

Abstract read
In one paragraph

Article in ACS omega, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Francisco Das Chagas Pereira de AndradeLaboratory of Innovation in Science and Technology - LACITEC, Department of Biophysics and Physiology, Federal University of Piauí, Teresina, Piauí 64049-550, Brazil.ORCID https://orcid.org/0000-0003-0141-2341
Yago Ferreira E SilvaPrograma de Computação Científica, Vice-Presidência de Educação, Informação e Comunicação, Fundação Oswaldo Cruz, Av. Brasil 4365, Residência Oficial, Manguinhos, Rio de Janeiro 21045-900, Brasil.ORCID https://orcid.org/0009-0005-2781-1203
Paulo Ricardo BatistaPrograma de Computação Científica, Vice-Presidência de Educação, Informação e Comunicação, Fundação Oswaldo Cruz, Av. Brasil 4365, Residência Oficial, Manguinhos, Rio de Janeiro 21045-900, Brasil.ORCID https://orcid.org/0000-0002-3399-174X
Anderson Nogueira MendesLaboratory of Innovation in Science and Technology - LACITEC, Department of Biophysics and Physiology, Federal University of Piauí, Teresina, Piauí 64049-550, Brazil.ORCID https://orcid.org/0000-0002-9778-3667

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Integrins are essential transmembrane receptors that mediate bidirectional signaling between the extracellular matrix (ECM) and the cytoskeleton. Among them, αvβ3 and α5β1 are key regulators of angiogenesis, metastasis, and tumor progression. The laminin-1-derived C16 peptide (KAFDITYVRLKF) interacts with both integrins, but the molecular determinants governing its specificity remain unclear. Here, we applied an integrative computational approach combining ADMET predictions, molecular docking, and all-atom molecular dynamics (MD) simulations to characterize C16 pharmacokinetics and its predicted binding modes to αvβ3 and α5β1.

Identifiers

PMID41799060
PMCPMC12961469

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.