Evidence map›Paper›PMID 41799030›Full record

ArticleBioMedicine2026

Neurosurgical management of pineal lesions: Insights from a single-center study of 27 cases.

David Montesinos Contreras, Walter Stummer, Maryam Khaleghi Ghadiri

Abstract read
In one paragraph

Article in BioMedicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

David Montesinos ContrerasKlinik für Neurochirurgie, Münster University, 48149, Münster, Germany.
Walter StummerKlinik für Neurochirurgie, Münster University, 48149, Münster, Germany.
Maryam Khaleghi GhadiriKlinik für Neurochirurgie, Münster University, 48149, Münster, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Pineal lesions are rare and surgically challenging due to their deep location, histological diversity, and potential malignancy. The complexity of the pineal region anatomy and the diverse pathological spectrum contribute to the lack of standardized treatment strategies, making appropriate management controversial. Aim: This study aimed to evaluate the surgical outcomes of patients with pineal tumors or cysts and to assess the impact of different surgical approaches, particularly the extent of resection, on progression-free survival. Methods: We conducted a retrospective analysis of 27 patients treated for pineal tumors or cysts at our institution between 2010 and 2020. Data regarding clinical presentation, surgical technique, extent of resection, pathological diagnosis, and follow-up outcomes were collected and analyzed. Surgical outcomes were compared between patients undergoing biopsy and those receiving varying degrees of tumor resection. Results: Our analyses suggest that total resection could be the most effective approach for reducing the risk of tumor recurrence. Furthermore, our findings indicate that histological subtype is a statistically significant predictor of progression-free survival in patients. Conclusion: Our findings suggest that achieving a greater extent of resection, when safely feasible, may contribute to improved long-term outcomes. These results emphasize the need for larger, multicenter studies to further optimize treatment strategies for these complex lesions.

Indexed as

BrainCancerLesionPineal gland tumorsPineal regionTumor surgery

Identifiers

PMID41799030
PMCPMC12962756

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.